Literature DB >> 16174873

Molecular pathways leading to cancer cachexia.

Michael J Tisdale1.   

Abstract

Loss of body weight in cancer patients strongly influences morbidity and mortality. Recent studies have suggested that both tumor and host factors play a major role in tissue catabolism in cachexia, leading to upregulation of degradative pathways in both skeletal muscle and adipose tissue.

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Year:  2005        PMID: 16174873     DOI: 10.1152/physiol.00019.2005

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN: 1548-9221


  50 in total

1.  The dose-dependent effects of endotoxin on protein metabolism in two types of rat skeletal muscle.

Authors:  Miroslav Kovarik; Tomas Muthny; Ludek Sispera; Milan Holecek
Journal:  J Physiol Biochem       Date:  2012-02-07       Impact factor: 4.158

Review 2.  Pathogenesis of muscle wasting in cancer cachexia: targeted anabolic and anticatabolic therapies.

Authors:  Kimberlee Burckart; Sorin Beca; Randall J Urban; Melinda Sheffield-Moore
Journal:  Curr Opin Clin Nutr Metab Care       Date:  2010-07       Impact factor: 4.294

3.  Impact of cachexia on pharmacokinetic disposition of and clinical responses to oxycodone in cancer patients.

Authors:  Takafumi Naito; Masaki Tashiro; Keisuke Yamamoto; Kazunori Ohnishi; Yoshiyuki Kagawa; Junichi Kawakami
Journal:  Eur J Clin Pharmacol       Date:  2012-03-23       Impact factor: 2.953

Review 4.  Energy homeostasis and cachexia in chronic kidney disease.

Authors:  Robert H Mak; Wai Cheung
Journal:  Pediatr Nephrol       Date:  2006-08-01       Impact factor: 3.714

Review 5.  Understanding cancer-induced cachexia: imaging the flame and its fuel.

Authors:  Marie-France Penet; Paul T Winnard; Michael A Jacobs; Zaver M Bhujwalla
Journal:  Curr Opin Support Palliat Care       Date:  2011-12       Impact factor: 2.302

6.  Increased hypoxia-inducible factor-1α in striated muscle of tumor-bearing mice.

Authors:  Raymond D Devine; Sabahattin Bicer; Peter J Reiser; Loren E Wold
Journal:  Am J Physiol Heart Circ Physiol       Date:  2017-03-24       Impact factor: 4.733

7.  Insulin secretion decline in Walker-256 tumor-bearing rats is early, follows the course of cachexia, and is not improved by lixisenatide.

Authors:  Débora Luiza Quintilhano; Daniele Romani Miksza; Winny Beatriz de Souza Galia; Mahira Oliveira Ramalho Costa Ramalho; Camila Ferraz Lucena; Maíra Mello Rezende Valle; Maria Fernanda Rodrigues Graciano; Helenir Medri de Souza; Gisele Lopes Bertolini
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2020-10-31       Impact factor: 3.000

Review 8.  Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer.

Authors:  R J DeBerardinis; T Cheng
Journal:  Oncogene       Date:  2009-11-02       Impact factor: 9.867

Review 9.  Factors contributing to muscle wasting and dysfunction in COPD patients.

Authors:  Rob C I Wüst; Hans Degens
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2007

10.  Association of interleukin-8 with cachexia from patients with low-third gastric cancer.

Authors:  Bo Song; Dianliang Zhang; Shuchun Wang; Hongmei Zheng; Xinxiang Wang
Journal:  Comp Funct Genomics       Date:  2009-11-23
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