Literature DB >> 16172695

Combining benzo[d]isoselenazol-3-ones with sterically hindered alicyclic amines and nitroxides: enhanced activity as glutathione peroxidase mimics.

Tamas Kálai1, Govindasamy Mugesh, Gouriprasanna Roy, Helmut Sies, Zoltán Berente, Kálmán Hideg.   

Abstract

Benzo[d]isoselenazol-3-ones N-substituted with sterically hindered diamagnetic and paramagnetic five- or six-membered nitroxides or their precursors, including ring-opened diselenides, exhibit synergism in glutathione peroxidase (GPx) activity.

Entities:  

Mesh:

Substances:

Year:  2005        PMID: 16172695     DOI: 10.1039/b509865c

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  4 in total

1.  Synthesis and functional survey of new Tacrine analogs modified with nitroxides or their precursors.

Authors:  Tamás Kálai; Robin Altman; Izumi Maezawa; Mária Balog; Christophe Morisseau; Jitka Petrlova; Bruce D Hammock; Lee-Way Jin; James R Trudell; John C Voss; Kálmán Hideg
Journal:  Eur J Med Chem       Date:  2014-03-12       Impact factor: 6.514

2.  Synthesis and study of new paramagnetic and diamagnetic verapamil derivatives.

Authors:  Balázs Bognár; Shabnam Ahmed; M Lakshmi Kuppusamy; Karuppaiyah Selvendiran; Mahmood Khan; József Jeko; Olga H Hankovszky; Tamás Kálai; Periannan Kuppusamy; Kálmán Hideg
Journal:  Bioorg Med Chem       Date:  2010-02-25       Impact factor: 3.641

3.  Convergent Synthesis of Two Fluorescent Ebselen-Coumarin Heterodimers.

Authors:  Jim Küppers; Anna Christina Schulz-Fincke; Jerzy Palus; Mirosław Giurg; Jacek Skarżewski; Michael Gütschow
Journal:  Pharmaceuticals (Basel)       Date:  2016-07-08

Review 4.  Novel multitarget-directed tacrine derivatives as potential candidates for the treatment of Alzheimer's disease.

Authors:  Wen-Yu Wu; Yu-Chen Dai; Nian-Guang Li; Ze-Xi Dong; Ting Gu; Zhi-Hao Shi; Xin Xue; Yu-Ping Tang; Jin-Ao Duan
Journal:  J Enzyme Inhib Med Chem       Date:  2017-12       Impact factor: 5.051

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.