Literature DB >> 16172680

Lactone-free ginkgolides via regioselective DIBAL-H reduction.

Hideki Ishii1, Sergei V Dzyuba, Koji Nakanishi.   

Abstract

The lactone rings of ginkgolide A are converted into corresponding tetrahydrofuran moieties via DIBAL-H reduction followed by deoxygenation of the formed lactols with Et3SiH-BF3.Et2O to produce a series of lactone-free ginkgolides.

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Year:  2005        PMID: 16172680     DOI: 10.1039/b509129b

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  1 in total

1.  Protection against beta-amyloid induced abnormal synaptic function and cell death by Ginkgolide J.

Authors:  Ottavio Vitolo; Bing Gong; Zixuan Cao; Hideki Ishii; Stanislav Jaracz; Koji Nakanishi; Ottavio Arancio; Sergei V Dzyuba; Roger Lefort; Michael Shelanski
Journal:  Neurobiol Aging       Date:  2007-07-20       Impact factor: 4.673

  1 in total

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