B J Schmidt1. 1. Section of Neurology, Department of Internal Medicine, Faculty of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Abstract
STUDY DESIGN: Case report of a patient with subacute delayed myelopathy after an acute low thoracic spine injury. OBJECTIVES: To draw awareness to a rarely described complication with potential to add devastating neurological insult to the original spinal cord injury, and to discuss evidence supporting a vascular mechanism. SETTING: Health Science Centre, Winnipeg, Manitoba, Canada. CASE REPORT: A 35-year-old woman developed clinical and MRI evidence of ascending myelopathy, extending up to C5, 16 days after a T11/12 fracture dislocation. The distribution of MRI signal abnormality, MRI evidence of prominent venous markings, and association with upright mobilization and the wearing of a thoraco-lumbo-sacral orthosis, suggest that elevated spinal venous pressure in conjunction with low arterial pressure may have induced impaired spinal cord vascular perfusion. CONCLUSION: After recent spinal cord injury, factors exacerbating spinal venous hypertension and/or arterial hypotension may in some patients lead to impaired spinal cord perfusion. These factors should be considered and corrected if symptoms or signs of progressive myelopathy emerge in the first few days or weeks after injury. Spinal Cord (2006) 44, 322-325. doi:10.1038/sj.sc.3101801; published online 20 September 2005.
STUDY DESIGN: Case report of a patient with subacute delayed myelopathy after an acute low thoracic spine injury. OBJECTIVES: To draw awareness to a rarely described complication with potential to add devastating neurological insult to the original spinal cord injury, and to discuss evidence supporting a vascular mechanism. SETTING: Health Science Centre, Winnipeg, Manitoba, Canada. CASE REPORT: A 35-year-old woman developed clinical and MRI evidence of ascending myelopathy, extending up to C5, 16 days after a T11/12 fracture dislocation. The distribution of MRI signal abnormality, MRI evidence of prominent venous markings, and association with upright mobilization and the wearing of a thoraco-lumbo-sacral orthosis, suggest that elevated spinal venous pressure in conjunction with low arterial pressure may have induced impaired spinal cord vascular perfusion. CONCLUSION: After recent spinal cord injury, factors exacerbating spinal venous hypertension and/or arterial hypotension may in some patients lead to impaired spinal cord perfusion. These factors should be considered and corrected if symptoms or signs of progressive myelopathy emerge in the first few days or weeks after injury. Spinal Cord (2006) 44, 322-325. doi:10.1038/sj.sc.3101801; published online 20 September 2005.