| Literature DB >> 16171944 |
Roppei Yamada1, Syunsuke Yanoma, Makoto Akaike, Akira Tsuburaya, Yukio Sugimasa, Shoji Takemiya, Hisahiko Motohashi, Yasushi Rino, Yoshinori Takanashi, Toshio Imada.
Abstract
Negative ions are considered to have potential health benefits, but few studies have examined their effects in vivo. We studied water-generated negative ions (WNI) with respect to physical properties as well as immunologic activation and anti-tumor activity (inhibition of carcinogenesis and tumor growth) in mice. Electrically, generated negative ions (ENI) served as control. Water-generated negative ions had a long life, significantly enhanced the cytotoxic activity of natural killer cells, and significantly decreased the incidence of cancer and inhibited tumor growth. Anti-tumor effects were attributed to enhancement of natural killer cell activity. The mechanisms and applications of negative ions warrant further investigation.Entities:
Mesh：
Substances：
Year: 2005 PMID： 16171944 DOI： 10.1016/j.canlet.2005.08.002
Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679