Literature DB >> 1617167

Viral antigen presentation and MHC assembly.

T J Braciale1, V L Braciale.   

Abstract

Viruses and other intracellular pathogens represent a unique challenge to the vertebrate immune system. To deal with this problem of intracellular invasion the immune system has developed an elegant strategy to mark virally infected cells. This review discusses current issues relating to the cell biology of MHC molecule assembly and antigen presentation events from the standpoint of viruses and anti-viral immunity.

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Year:  1992        PMID： 1617167

Source DB:  PubMed          Journal:  Semin Immunol        ISSN： 1044-5323            Impact factor:   11.130


  7 in total

1.  A lung-specific neo-antigen elicits specific CD8+ T cell tolerance with preserved CD4+ T cell reactivity. Implications for immune-mediated lung disease.

Authors:  R I Enelow; M H Stoler; A Srikiatkhachorn; C Kerlakian; S Agersborg; J A Whitsett; T J Braciale
Journal:  J Clin Invest       Date:  1996-08-15       Impact factor: 14.808

Review 2.  The self and the nonself: immunorecognition and immunologic functions.

Authors:  P del Guercio
Journal:  Immunol Res       Date:  1993       Impact factor: 2.829

3.  Interleukin-3 and granulocyte-macrophage colony-stimulating factor enhance the generation and function of dendritic cells.

Authors:  E Storozynsky; J G Woodward; J G Frelinger; E M Lord
Journal:  Immunology       Date:  1999-05       Impact factor: 7.397

4.  Role of human papillomavirus in determining the HLA associated risk of cervical carcinogenesis.

Authors:  W Z Mehal; Y M Lo; C S Herrington; M F Evans; M C Papadopoulos; K Odunis; T S Ganesan; J O McGee; J I Bell; K A Fleming
Journal:  J Clin Pathol       Date:  1994-12       Impact factor: 3.411

5.  Enhanced intracellular dissociation of major histocompatibility complex class I-associated peptides: a mechanism for optimizing the spectrum of cell surface-presented cytotoxic T lymphocyte epitopes.

Authors:  A J Sijts; E G Pamer
Journal:  J Exp Med       Date:  1997-04-21       Impact factor: 14.307

6.  Virus-specific CD8+ T lymphocytes downregulate T helper cell type 2 cytokine secretion and pulmonary eosinophilia during experimental murine respiratory syncytial virus infection.

Authors:  A Srikiatkhachorn; T J Braciale
Journal:  J Exp Med       Date:  1997-08-04       Impact factor: 14.307

7.  Targeting of HIV-1 antigens for rapid intracellular degradation enhances cytotoxic T lymphocyte (CTL) recognition and the induction of de novo CTL responses in vivo after immunization.

Authors:  T W Tobery; R F Siliciano
Journal:  J Exp Med       Date:  1997-03-03       Impact factor: 14.307
  7 in total

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