STUDY OBJECTIVES: The steep decline in slow-wave (delta) electroencephalogram (EEG) intensity across adolescence is a prominent feature of late brain maturation. As a first step in determining whether the adolescent delta decline is similar in both sexes, we compared cross-sectional sleep EEG data from 9- and 12-year-old boys and girls. DESIGN: All-night EEG recordings, 6 months apart, were conducted on each subject. SETTING: EEG was recorded in the subjects' homes. PARTICIPANTS: Thirty-two 9-year-olds and 38 12-year-olds are enrolled in a 4-year longitudinal study of adolescent sleep. There are equal numbers of each sex in both age cohorts. INTERVENTIONS: N/A. MEASUREMENTS: Using ambulatory recorders, EEG was recorded in the subjects' homes on their normal sleep schedule. For each of the 2 semi-annual recording periods, data from the 10 subjects from each age-sex group with the cleanest (fewest artifacts) signals were selected for crosssectional comparisons of visual scoring and EEG variables. All artifact-free 20-second non-rapid eye movement epochs were analyzed with power spectral and period-amplitude analysis. RESULTS: In the 12-year-old cohort, delta power per minute was 37% higher in boys than girls. The 9-year-old cohort showed no sex difference. A second recording 6 months later produced similar results. CONCLUSION: These cross-sectional data indicate that girls begin the steep adolescent decline in slow-wave EEG earlier than boys. We hypothesize that this reflects an earlier onset of adolescent synaptic pruning in females.
STUDY OBJECTIVES: The steep decline in slow-wave (delta) electroencephalogram (EEG) intensity across adolescence is a prominent feature of late brain maturation. As a first step in determining whether the adolescent delta decline is similar in both sexes, we compared cross-sectional sleep EEG data from 9- and 12-year-old boys and girls. DESIGN: All-night EEG recordings, 6 months apart, were conducted on each subject. SETTING: EEG was recorded in the subjects' homes. PARTICIPANTS: Thirty-two 9-year-olds and 38 12-year-olds are enrolled in a 4-year longitudinal study of adolescent sleep. There are equal numbers of each sex in both age cohorts. INTERVENTIONS: N/A. MEASUREMENTS: Using ambulatory recorders, EEG was recorded in the subjects' homes on their normal sleep schedule. For each of the 2 semi-annual recording periods, data from the 10 subjects from each age-sex group with the cleanest (fewest artifacts) signals were selected for crosssectional comparisons of visual scoring and EEG variables. All artifact-free 20-second non-rapid eye movement epochs were analyzed with power spectral and period-amplitude analysis. RESULTS: In the 12-year-old cohort, delta power per minute was 37% higher in boys than girls. The 9-year-old cohort showed no sex difference. A second recording 6 months later produced similar results. CONCLUSION: These cross-sectional data indicate that girls begin the steep adolescent decline in slow-wave EEG earlier than boys. We hypothesize that this reflects an earlier onset of adolescent synaptic pruning in females.
Authors: J N Giedd; J Blumenthal; N O Jeffries; F X Castellanos; H Liu; A Zijdenbos; T Paus; A C Evans; J L Rapoport Journal: Nat Neurosci Date: 1999-10 Impact factor: 24.884
Authors: T Hori; Y Sugita; E Koga; S Shirakawa; K Inoue; S Uchida; H Kuwahara; M Kousaka; T Kobayashi; Y Tsuji; M Terashima; K Fukuda; N Fukuda Journal: Psychiatry Clin Neurosci Date: 2001-06 Impact factor: 5.188
Authors: M D De Bellis; M S Keshavan; S R Beers; J Hall; K Frustaci; A Masalehdan; J Noll; A M Boring Journal: Cereb Cortex Date: 2001-06 Impact factor: 5.357
Authors: Ian G Campbell; Nato Darchia; Lisa M Higgins; Igor V Dykan; Nicole M Davis; Evan de Bie; Irwin Feinberg Journal: Sleep Date: 2011-01-01 Impact factor: 5.849
Authors: Andrew W McHill; Elizabeth B Klerman; Bridgette Slater; Tairmae Kangarloo; Piotr W Mankowski; Natalie D Shaw Journal: Sleep Date: 2017-03-01 Impact factor: 5.849
Authors: Ignacio E Tapia; Laurie Karamessinis; Preetam Bandla; Jingtao Huang; Andrea Kelly; Michelle Pepe; Brian Schultz; Paul Gallagher; Lee J Brooks; Carole L Marcus Journal: Sleep Date: 2008-12 Impact factor: 5.849
Authors: Fiona C Baker; Adrian R Willoughby; Massimiliano de Zambotti; Peter L Franzen; Devin Prouty; Harold Javitz; Brant Hasler; Duncan B Clark; Ian M Colrain Journal: Sleep Date: 2016-07-01 Impact factor: 5.849