Literature DB >> 16170604

Serodiagnosis of mycoses using recombinant antigens.

Natalia Elguezabal1, Fernando Lopitz-Otsoa, Ana Laín, Iñigo Fernández de Larrinoa, María Dolores Moragues, José Pontón.   

Abstract

The early diagnosis of mycoses is important for the institution of an effective antifungal therapy. Detection of antibodies against crude antigenic extracts is one of the standard techniques for the diagnosis of most mycoses. However, while these crude antigenic extracts are relatively easy to obtain, they usually show low reproducibility and are not very specific, since antibodies from patients with different mycoses may show cross-reactivity. The application of molecular biology techniques to the study of fungal antigens has allowed the production of recombinant antigens that may help to solve these problems. The purpose of this review is to discuss the use of recombinant fungal antigens in the diagnosis of mycoses.

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Year:  2005        PMID： 16170604     DOI： 10.1007/s11046-005-0144-9

Source DB:  PubMed          Journal:  Mycopathologia        ISSN： 0301-486X            Impact factor:   2.574


  65 in total

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Authors:  R Puccia; L R Travassos
Journal:  J Clin Microbiol       Date:  1991-08       Impact factor: 5.948

2.  Expression in bacteria of the gene encoding the gp43 antigen of paracoccidioides brasiliensis: immunological reactivity of the recombinant fusion proteins.

Authors:  Susana N Diniz; Kátia C Carvalho; Patrícia S Cisalpino; José F Silveira; Luiz R Travassos; Rosana Puccia
Journal:  Clin Diagn Lab Immunol       Date:  2002-11

3.  Characterization of AFMP1: a novel target for serodiagnosis of aspergillosis.

Authors:  K Y Yuen; C M Chan; K M Chan; P C Woo; X Y Che; A S Leung; L Cao
Journal:  J Clin Microbiol       Date:  2001-11       Impact factor: 5.948

4.  Recombinant Coccidioides immitis complement-fixing antigen: detection of an epitope shared by C. immitis, Histoplasma capsulatum, and Blastomyces dermatitidis.

Authors:  M C Yang; D M Magee; L Kaufman; Y Zhu; R A Cox
Journal:  Clin Diagn Lab Immunol       Date:  1997-01

5.  Selective cloning of allergens from the skin colonizing yeast Malassezia furfur by phage surface display technology.

Authors:  M Lindborg; C G Magnusson; A Zargari; M Schmidt; A Scheynius; R Crameri; P Whitley
Journal:  J Invest Dermatol       Date:  1999-08       Impact factor: 8.551

6.  Use of the 27-kilodalton recombinant protein from Paracoccidioides brasiliensis in serodiagnosis of paracoccidioidomycosis.

Authors:  B L Ortiz; S Díez; M E Urán; J M Rivas; M Romero; V Caicedo; A Restrepo; J G McEwen
Journal:  Clin Diagn Lab Immunol       Date:  1998-11

Review 7.  Current status of nonculture methods for diagnosis of invasive fungal infections.

Authors:  Siew Fah Yeo; Brian Wong
Journal:  Clin Microbiol Rev       Date:  2002-07       Impact factor: 26.132

8.  Molecular cloning, characterization and expression of the heat shock protein 60 gene from the human pathogenic fungus Paracoccidioides brasiliensis.

Authors:  S M Izacc; F J Gomez; R S Jesuino; C A Fonseca; M S Felipe; G S Deepe; C M Soares
Journal:  Med Mycol       Date:  2001-10       Impact factor: 4.076

9.  Selective expression of a major allergen and cytotoxin, Asp f I, in Aspergillus fumigatus. Implications for the immunopathogenesis of Aspergillus-related diseases.

Authors:  L K Arruda; B J Mann; M D Chapman
Journal:  J Immunol       Date:  1992-11-15       Impact factor: 5.422

10.  Characterization of a novel Candida albicans 29 kDa IgE-binding protein--purification, cDNA isolation and heterologous expression of Cand a 3.

Authors:  H Chou; M F Tam; C-Y Chang; H-Y Lai; M-H Huang; C-T Chou; S-S Lee; H-D Shen
Journal:  Allergy       Date:  2003-11       Impact factor: 13.146
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  3 in total

1.  Garlic alters the expression of putative virulence factor genes SIR2 and ECE1 in vulvovaginal C. albicans isolates.

Authors:  Mohamed M Said; Cathy Watson; Danilla Grando
Journal:  Sci Rep       Date:  2020-02-27       Impact factor: 4.379

2.  Diagnosis of invasive candidiasis by enzyme-linked immunosorbent assay using the N-terminal fragment of Candida albicans hyphal wall protein 1.

Authors:  Ana Laín; Natalia Elguezabal; Sonia Brena; Juan Carlos García-Ruiz; Amalia Del Palacio; María D Moragues; José Pontón
Journal:  BMC Microbiol       Date:  2007-04-21       Impact factor: 3.605

Review 3.  Use of recombinant antigens for the diagnosis of invasive candidiasis.

Authors:  Ana Laín; Natalia Elguezabal; Elena Amutio; Iñigo Fernández de Larrinoa; María Dolores Moragues; José Pontón
Journal:  Clin Dev Immunol       Date:  2008
  3 in total

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