José M López1, Eveline Oestreicher. 1. Departamento de Endocrinología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. jmlopez@med.puc.cl
Abstract
OBJECTIVE: To determine the response to tamoxifen in a woman with hypogonadotropic hypogonadism induced by hyperprolactinemia resistant to dopamine agonist drugs. DESIGN: Case report. SETTING: Academic fertility center. PATIENT(S): A young woman with persistent amenorrhea, symptomatic hypogonadotropic hypogonadism, and hyperprolactinemia. INTERVENTION(S): Tamoxifen was administered in addition to bromocriptine. MAIN OUTCOME MEASURE(S): Measurements of follicle-stimulating hormone, estradiol, prolactin, and progesterone. RESULT(S): Recovery of gonadal-hypothalamic-pituitary axis. CONCLUSION(S): Tamoxifen can revert the effects of chronic hypogonadotropic hypogonadism induced by hyperprolactinemia resistant to dopamine agonists.
OBJECTIVE: To determine the response to tamoxifen in a woman with hypogonadotropic hypogonadism induced by hyperprolactinemia resistant to dopamine agonist drugs. DESIGN: Case report. SETTING: Academic fertility center. PATIENT(S): A young woman with persistent amenorrhea, symptomatic hypogonadotropic hypogonadism, and hyperprolactinemia. INTERVENTION(S): Tamoxifen was administered in addition to bromocriptine. MAIN OUTCOME MEASURE(S): Measurements of follicle-stimulating hormone, estradiol, prolactin, and progesterone. RESULT(S): Recovery of gonadal-hypothalamic-pituitary axis. CONCLUSION(S): Tamoxifen can revert the effects of chronic hypogonadotropic hypogonadism induced by hyperprolactinemia resistant to dopamine agonists.
Authors: Kwangsik Nho; Vijay K Ramanan; Emrin Horgusluoglu; Sungeun Kim; Mark H Inlow; Shannon L Risacher; Brenna C McDonald; Martin R Farlow; Tatiana M Foroud; Sujuan Gao; Christopher M Callahan; Hugh C Hendrie; Alexander B Niculescu; Andrew J Saykin Journal: J Alzheimers Dis Date: 2015 Impact factor: 4.472