| Literature DB >> 1616936 |
T G St Pierre1, D R Richardson, E Baker, J Webb.
Abstract
Human melanoma and rat hepatoma cells cultured in the presence of low concentrations (2.5 microM) of low-molecular-weight iron (Fe) chelates and Fe-transferrin complexes have been studied with 57Fe Mössbauer spectroscopy. The spectra show that holoferritin is only a minor fraction of the total iron present in the cells. The major form of Fe was in a low-spin state unlike the high-spin Fe(III) found in ferritin. Only about 10% of the Fe could be attributed to ferritin. In addition, the hepatoma cells had a high-spin Fe(II) spectral component which made up about 20% of the Fe present.Entities:
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Year: 1992 PMID： 1616936 DOI： 10.1016/0167-4889(92)90131-t
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002