Literature DB >> 16168367

The continuing saga of p53--more sleepless nights ahead.

Carol Prives1, James J Manfredi.   

Abstract

Despite previous assumptions that the tumor suppressor protein p53 exists primarily and functionally as a single species, recent papers document the existence and unexpected properties of numerous p53 isoforms in cells. The complexity of p53 continues to unfold.

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Year:  2005        PMID： 16168367     DOI： 10.1016/j.molcel.2005.08.024

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  8 in total

1.  The novel p53 isoform "delta p53" is a misfolded protein and does not bind the p21 promoter site.

Authors:  Maria M García-Alai; Henning Tidow; Eviatar Natan; Fiona M Townsley; Dmitry B Veprintsev; Alan R Fersht
Journal:  Protein Sci       Date:  2008-07-11       Impact factor: 6.725

2.  p53 and the PWWP domain containing effector proteins in chromatin damage repair.

Authors:  Jing Hu; Yanming Wang
Journal:  Cell Dev Biol       Date:  2013-05-10

3.  The Levels of H11/HspB8 DNA methylation in human melanoma tissues and xenografts are a critical molecular marker for 5-Aza-2'-deoxycytidine therapy.

Authors:  Cynthia C Smith; Baiquan Li; Juan Liu; Kie-Sok Lee; Laure Aurelian
Journal:  Cancer Invest       Date:  2011-07       Impact factor: 2.176

Review 4.  Tumor suppression by p53: making cells senescent.

Authors:  Yingjuan Qian; Xinbin Chen
Journal:  Histol Histopathol       Date:  2010-04       Impact factor: 2.303

5.  The p73 tumor suppressor is targeted by Pirh2 RING finger E3 ubiquitin ligase for the proteasome-dependent degradation.

Authors:  Yong-Sam Jung; Yingjuan Qian; Xinbin Chen
Journal:  J Biol Chem       Date:  2011-08-18       Impact factor: 5.157

6.  Expression of genes related to apoptosis, cell cycle and signaling pathways are independent of TP53 status in urinary bladder cancer cells.

Authors:  Glenda N da Silva; Adriane F Evangelista; Danielle A Magalhães; Cláudia Macedo; Michelle C Búfalo; Elza T Sakamoto-Hojo; Geraldo A S Passos; Daisy M F Salvadori
Journal:  Mol Biol Rep       Date:  2010-11-30       Impact factor: 2.316

7.  Expression of full-length p53 and its isoform Deltap53 in breast carcinomas in relation to mutation status and clinical parameters.

Authors:  Lars O Baumbusch; Simen Myhre; Anita Langerød; Anna Bergamaschi; Stephanie B Geisler; Per E Lønning; Wolfgang Deppert; Irene Dornreiter; Anne-Lise Børresen-Dale
Journal:  Mol Cancer       Date:  2006-10-20       Impact factor: 27.401

8.  Connection between Cell Phone use, p53 Gene Expression in Different Zones of Glioblastoma Multiforme and Survival Prognoses.

Authors:  Reza Akhavan-Sigari; Morteza Mazloum Farsi Baf; Vahid Ariabod; Veit Rohde; Saeed Rahighi
Journal:  Rare Tumors       Date:  2014-08-08
  8 in total

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