| Literature DB >> 16165013 |
Jeroen Hagendoorn1, Timothy P Padera, Dai Fukumura, Rakesh K Jain.
Abstract
Inhibition of lymphangiogenesis prevents lymphatic cancer metastasis, whereas induction of lymphangiogenesis alleviates lymphedema in experimental animal models. The number of known molecular players that govern the formation and function of the microlymphatic system is growing. Here, we review the role of nitric oxide within the regulation of lymphatic formation and function and point out key unanswered questions for its translation into clinical therapy.Entities:
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Year: 2005 PMID： 16165013 DOI： 10.1016/j.tcm.2005.06.003
Source DB: PubMed Journal: Trends Cardiovasc Med ISSN： 1050-1738 Impact factor: 6.677