Literature DB >> 16162962

Functional role of the 503F variant of the organic cation transporter OCTN1 in Crohn's disease.

D Taubert, G Grimberg, N Jung, A Rubbert, E Schömig.   

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Year:  2005        PMID： 16162962      PMCID： PMC1774715          DOI： 10.1136/gut.2005.076083

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


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3.  Functional variants of OCTN cation transporter genes are associated with Crohn disease.

Authors:  Vanya D Peltekova; Richard F Wintle; Laurence A Rubin; Christopher I Amos; Qiqing Huang; Xiangjun Gu; Bill Newman; Mark Van Oene; David Cescon; Gordon Greenberg; Anne M Griffiths; Peter H St George-Hyslop; Katherine A Siminovitch
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Review 4.  The key role of macrophages in the immunopathogenesis of inflammatory bowel disease.

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Journal:  Inflamm Bowel Dis       Date:  2000-02       Impact factor: 5.325

Review 5.  Recent advances in the genetics of inflammatory bowel disease.

Authors:  Bill Newman; Katherine A Siminovitch
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6.  Discovery of the ergothioneine transporter.

Authors:  Dirk Gründemann; Stephanie Harlfinger; Stefan Golz; Andreas Geerts; Andreas Lazar; Reinhard Berkels; Norma Jung; Andrea Rubbert; Edgar Schömig
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7.  Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease.

Authors:  H-P Török; J Glas; L Tonenchi; P Lohse; B Müller-Myhsok; O Limbersky; C Neugebauer; F Schnitzler; J Seiderer; C Tillack; S Brand; G Brünnler; P Jagiello; J T Epplen; T Griga; W Klein; U Schiemann; M Folwaczny; T Ochsenkühn; C Folwaczny
Journal:  Gut       Date:  2005-06-14       Impact factor: 23.059

8.  An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.

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1.  Crohn's disease and genetic hitchhiking at IBD5.

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Journal:  Mol Biol Evol       Date:  2011-08-04       Impact factor: 16.240

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4.  Combination Metabolomics Approach for Identifying Endogenous Substrates of Carnitine/Organic Cation Transporter OCTN1.

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5.  Wide tolerance to amino acids substitutions in the OCTN1 ergothioneine transporter.

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6.  Decreased proliferation and erythroid differentiation of K562 cells by siRNA-induced depression of OCTN1 (SLC22A4) transporter gene.

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7.  The unusual amino acid L-ergothioneine is a physiologic cytoprotectant.

Authors:  B D Paul; S H Snyder
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Review 8.  Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications.

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10.  Identification and determination of selenoneine, 2-selenyl-N α , N α , N α -trimethyl-L-histidine, as the major organic selenium in blood cells in a fish-eating population on remote Japanese Islands.

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