Literature DB >> 16161002

Experimental spinal cord repair (by means of direct connection of the above-the-lesion CNS with PNS).

G A Brunelli1, G R Brunelli, V Mattiuzzo.   

Abstract

There are no medical or surgical treatments able to repair traumatic paraplegia. Experiments done by connecting the above-the-lesion with the below-the-lesion cord by means of PNS grafts have always failed. The grafts are reinhabited by regrowing axons of the first motoneurons which however are not able to progress into the distal spinal cord. At the present state of knowledge no surgical treatment can cure paraplegia. Thousands of researchers are working all over the world in many different types of research ranging from molecular biology to embriology, and from biochemistry to pharmacology and surgery. None of these experiments have proved to be practically effective.

Entities:  

Year:  1997        PMID: 16161002

Source DB:  PubMed          Journal:  Surg Technol Int        ISSN: 1090-3941


  2 in total

1.  Nerve allograft transplantation for functional restoration of the upper extremity: case series.

Authors:  Andrew I Elkwood; Neil R Holland; Spiros M Arbes; Michael I Rose; Matthew R Kaufman; Russell L Ashinoff; Mona A Parikh; Tushar R Patel
Journal:  J Spinal Cord Med       Date:  2011       Impact factor: 1.985

2.  Unsuspected plasticity of single neurons after connection of the corticospinal tract with peripheral nerves in spinal cord lesions.

Authors:  Giorgio Brunelli; Klaus von Wild
Journal:  J Korean Neurosurg Soc       Date:  2009-07-31
  2 in total

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