Literature DB >> 1616002

Gangliosides as modulators of cell function.

C B Zeller1, R B Marchase.   

Abstract

Gangliosides, sialic acid-containing glycosphingolipids, are found in the outer leaflet of the plasma membrane of all vertebrate tissues and species. This report presents a brief introduction to the gangliosides and reviews the chemistry and topography of their biosynthesis. It also presents an overview of the present evidence supporting a physiological significance for the gangliosides in a variety of experimental systems. This includes consideration of their potential roles in development and cell adhesion. In addition, experimental examples in which gangliosides appear to influence signal transduction processes through their interactions with plasma membrane proteins are discussed.

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Year:  1992        PMID： 1616002     DOI： 10.1152/ajpcell.1992.262.6.C1341

Source DB:  PubMed          Journal:  Am J Physiol        ISSN： 0002-9513


  27 in total

Review 1.  The role of globo-series glycolipids in neuronal cell differentiation--a review.

Authors:  T Ariga; R K Yu
Journal:  Neurochem Res       Date:  1998-03       Impact factor: 3.996

2.  Activities of glycolipid glycosyltransferases and sialidases during the early development of Xenopus laevis.

Authors:  R Gornati; S Basu; G Bernardini; A M Rizzo; F Rossi; B Berra
Journal:  Mol Cell Biochem       Date:  1997-01       Impact factor: 3.396

3.  Ionization and fragmentation of neutral and acidic glycosphingolipids with a Q-TOF mass spectrometer fitted with a MALDI ion source.

Authors:  V Hunnam; D J Harvey; D A Priestman; R H Bateman; R S Bordoli; R Tyldesley
Journal:  J Am Soc Mass Spectrom       Date:  2001-11       Impact factor: 3.109

4.  Properties of ganglioside GM1 in phosphatidylcholine bilayer membranes.

Authors:  R A Reed; G G Shipley
Journal:  Biophys J       Date:  1996-03       Impact factor: 4.033

5.  Targeting the GD3 acetylation pathway selectively induces apoptosis in glioblastoma.

Authors:  Suzanne M Birks; John Owusu Danquah; Linda King; Reinhardt Vlasak; Dariusz C Gorecki; Geoffrey J Pilkington
Journal:  Neuro Oncol       Date:  2011-07-31       Impact factor: 12.300

Review 6.  Glycosphingolipid degradation and animal models of GM2-gangliosidoses.

Authors:  T Kolter; K Sandhoff
Journal:  J Inherit Metab Dis       Date:  1998-08       Impact factor: 4.982

7.  A comparative assessment of TLC overlay technique and microwell adsorption assay in the examination of influenza A and Sendai virus specificities towards oligosaccharides and sialic acid linkages of gangliosides.

Authors:  J Müthing; F Unland
Journal:  Glycoconj J       Date:  1994-10       Impact factor: 2.916

8.  Expression of neutral glycosphingolipids and gangliosides in human skeletal and heart muscle determined by indirect immunofluorescence staining.

Authors:  M Cacić; J Müthing; I Kracun; U Neumann; S Weber-Schürholz
Journal:  Glycoconj J       Date:  1994-10       Impact factor: 2.916

Review 9.  GM2 ganglioside and pyramidal neuron dendritogenesis.

Authors:  S U Walkley; D A Siegel; K Dobrenis
Journal:  Neurochem Res       Date:  1995-11       Impact factor: 3.996

10.  Interaction of fibroblast growth factor-2 (FGF-2) with free gangliosides: biochemical characterization and biological consequences in endothelial cell cultures.

Authors:  M Rusnati; E Tanghetti; C Urbinati; G Tulipano; S Marchesini; M Ziche; M Presta
Journal:  Mol Biol Cell       Date:  1999-02       Impact factor: 4.138
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