| Literature DB >> 16157986 |
Tatsuya Suwabe1, Yoshifumi Ubara, Tetsuo Tagami, Naoki Sawa, Junichi Hoshino, Hideyuki Katori, Fumi Takemoto, Shigeko Hara, Kumi Aita, Shigeo Hara, Kenmei Takaichi.
Abstract
A 68-year-old woman was referred for evaluation of nephrotic-range proteinuria and a course suggesting rapidly progressive glomerulonephritis. Serum anti-neutrophil cytoplasmic antibody against myeloperoxidase (MPO) was 204 U/ml. A renal biopsy specimen revealed necrotizing glomerulonephritis with crescent formation. However, immunofluorescence showed staining with IgG and C3 along capillary walls. IgG positivity included both IgG1 and IgG4. Electron microscopic examination disclosed both paramesangial and subepithelial deposits. This case suggests that rarely, MPO-ANCA-related crescentic glomerulonephritis may present nephrotic-range proteinuria and show immune deposits along capillary walls.Entities:
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Year: 2005 PMID: 16157986 DOI: 10.2169/internalmedicine.44.853
Source DB: PubMed Journal: Intern Med ISSN: 0918-2918 Impact factor: 1.271