Literature DB >> 16157888

Statistical signals in bioinformatics.

Samuel Karlin1.   

Abstract

The Arthur M. Sackler Colloquium of the National Academy of Sciences, "Frontiers in Bioinformatics: Unsolved Problems and Challenges," organized by David Eisenberg, Russ Altman, and myself, was held October 15-17, 2004, to provide a forum for discussing concepts and methods in bioinformatics serving the biological and medical sciences. The deluge of genomic and proteomic data in the last two decades has driven the creation of tools that search and analyze biomolecular sequences and structures. Bioinformatics is highly interdisciplinary, using knowledge from mathematics, statistics, computer science, biology, medicine, physics, chemistry, and engineering.

Mesh：

Year:  2005        PMID： 16157888      PMCID： PMC1224616          DOI： 10.1073/pnas.0501804102

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  98 in total

1.  First and second moment of counts of words in random texts generated by Markov chains.

Authors:  J Kleffe; M Borodovsky
Journal:  Comput Appl Biosci       Date:  1992-10

2.  Methods and algorithms for statistical analysis of protein sequences.

Authors:  V Brendel; P Bucher; I R Nourbakhsh; B E Blaisdell; S Karlin
Journal:  Proc Natl Acad Sci U S A       Date:  1992-03-15       Impact factor: 11.205

3.  Basic local alignment search tool.

Authors:  S F Altschul; W Gish; W Miller; E W Myers; D J Lipman
Journal:  J Mol Biol       Date:  1990-10-05       Impact factor: 5.469

4.  Chance and statistical significance in protein and DNA sequence analysis.

Authors:  S Karlin; V Brendel
Journal:  Science       Date:  1992-07-03       Impact factor: 47.728

5.  An efficient algorithm for identifying matches with errors in multiple long molecular sequences.

Authors:  M Y Leung; B E Blaisdell; C Burge; S Karlin
Journal:  J Mol Biol       Date:  1991-10-20       Impact factor: 5.469

Review 6.  Patterns of DNA methylation--evolutionary vestiges of foreign DNA inactivation as a host defense mechanism. A proposal.

Authors:  W Doerfler
Journal:  Biol Chem Hoppe Seyler       Date:  1991-08

7.  Significant dispersed recurrent DNA sequences in the Escherichia coli genome. Several new groups.

Authors:  B E Blaisdell; K E Rudd; A Matin; S Karlin
Journal:  J Mol Biol       Date:  1993-02-20       Impact factor: 5.469

Review 8.  Organization of the bacterial chromosome.

Authors:  S Krawiec; M Riley
Journal:  Microbiol Rev       Date:  1990-12

9.  Human cytomegalovirus origin of DNA replication (oriLyt) resides within a highly complex repetitive region.

Authors:  M J Masse; S Karlin; G A Schachtel; E S Mocarski
Journal:  Proc Natl Acad Sci U S A       Date:  1992-06-15       Impact factor: 11.205

10.  Over- and under-representation of short oligonucleotides in DNA sequences.

Authors:  C Burge; A M Campbell; S Karlin
Journal:  Proc Natl Acad Sci U S A       Date:  1992-02-15       Impact factor: 11.205
View more
  9 in total

Review 1.  Statistics and bioinformatics in nutritional sciences: analysis of complex data in the era of systems biology.

Authors:  Wenjiang J Fu; Arnold J Stromberg; Kert Viele; Raymond J Carroll; Guoyao Wu
Journal:  J Nutr Biochem       Date:  2010-03-16       Impact factor: 6.048

2.  Distinctive features of large complex virus genomes and proteomes.

Authors:  Jan Mrázek; Samuel Karlin
Journal:  Proc Natl Acad Sci U S A       Date:  2007-03-09       Impact factor: 11.205

3.  Compressing proteomes: the relevance of medium range correlations.

Authors:  Dario Benedetto; Emanuele Caglioti; Claudia Chica
Journal:  EURASIP J Bioinform Syst Biol       Date:  2007

4.  A new database (GCD) on genome composition for eukaryote and prokaryote genome sequences and their initial analyses.

Authors:  Kirill Kryukov; Kenta Sumiyama; Kazuho Ikeo; Takashi Gojobori; Naruya Saitou
Journal:  Genome Biol Evol       Date:  2012-03-14       Impact factor: 3.416

5.  A two-step multiple-marker strategy for genome-wide association studies.

Authors:  Hugues Aschard; Mickaël Guedj; Florence Demenais
Journal:  BMC Proc       Date:  2007-12-18

6.  Screening of nucleotide variations in genomic sequences encoding charged protein regions in the human genome.

Authors:  Sabrine Belmabrouk; Najla Kharrat; Rania Abdelhedi; Amine Ben Ayed; Riadh Benmarzoug; Ahmed Rebai
Journal:  BMC Genomics       Date:  2017-08-08       Impact factor: 3.969

7.  Estimating statistical significance of local protein profile-profile alignments.

Authors:  Mindaugas Margelevičius
Journal:  BMC Bioinformatics       Date:  2019-08-13       Impact factor: 3.169

8.  Evolutionary conservation of orthoretroviral long terminal repeats (LTRs) and ab initio detection of single LTRs in genomic data.

Authors:  Farid Benachenhou; Patric Jern; Merja Oja; Göran Sperber; Vidar Blikstad; Panu Somervuo; Samuel Kaski; Jonas Blomberg
Journal:  PLoS One       Date:  2009-04-13       Impact factor: 3.240

9.  AT excursion: a new approach to predict replication origins in viral genomes by locating AT-rich regions.

Authors:  David S H Chew; Ming-Ying Leung; Kwok Pui Choi
Journal:  BMC Bioinformatics       Date:  2007-05-21       Impact factor: 3.169
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.