Literature DB >> 16157383

Liquid bandage (2-octyl cyanoacrylate) as a temporary wound barrier in clear corneal cataract surgery.

Seth W Meskin1, David C Ritterband, Daniel E Shapiro, Jaroslaw Kusmierczyk, Susan S Schneider, John A Seedor, Richard S Koplin.   

Abstract

PURPOSE: To determine the feasibility and side effect profile of 2-octyl cyanoacrylate with parabens (Liquid Bandage) as an adjunct wound sealant and barrier against the inflow of ocular surface fluid after clear corneal cataract surgery.
DESIGN: Prospective interventional case series. PARTICIPANTS: Fifty-one eyes of 51 patients undergoing clear corneal cataract surgery.
METHODS: Fifty-one eyes of 51 patients who underwent cataract surgery by one surgeon (RSK) were enrolled. A 2.75-mm clear corneal, triplanar, temporal incision was used in each case, followed by routine phacoemulsification. At the conclusion of each case, the wound was dried with a cellulose sponge. A modified microsponge with 1 to 2 drops of 2-octyl cyanoacrylate with parabens was then applied in a smooth layer to the wound. All wounds were rechecked for leakage with a cellulose sponge applied at the wound lip. The following criteria were evaluated on the first 2 postoperative visits: (1) visual acuity; (2) patient complaints; (3) wound integrity; (4) presence of tissue adhesive; and (5) any adverse events, including abnormal increase in local tissue reaction to the adhesive. MAIN OUTCOME MEASURES: Side effect profile and clinical course of 2-octyl cyanoacrylate with parabens applied to clear corneal wounds.
RESULTS: All 51 eyes demonstrated intraoperative watertight wound closure after the application of 2-octyl cyanoacrylate with parabens. Forty-five eyes (88%) had tissue adhesive still completely covering the wound on postoperative day 1. Two eyes (4%) had tissue adhesive over portions of their wound, and 4 eyes (8%) had no adhesive noted on their wound. All wounds were watertight on all postoperative visits. Thirty-one of 51 patients (61%) complained of mild transient foreign body sensation on postoperative day 1. Twenty-six patients (51%) had trace diffuse bulbar conjunctival hyperemia. Five patients had trace focal conjunctival hyperemia adjacent to the wound. Nine patients (18%) had remnants of the adhesive remaining on the second postoperative visit.
CONCLUSIONS: Our study demonstrates the ease of use and applicability and low side effect profile of 2-octyl cyanoacrylate with parabens as a temporary wound barrier in clear corneal cataract surgery.

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Year:  2005        PMID: 16157383     DOI: 10.1016/j.ophtha.2005.05.014

Source DB:  PubMed          Journal:  Ophthalmology        ISSN: 0161-6420            Impact factor:   12.079


  4 in total

Review 1.  Cataract surgery and methods of wound closure: a review.

Authors:  Cynthia Matossian; Sarah Makari; Richard Potvin
Journal:  Clin Ophthalmol       Date:  2015-05-22

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Authors:  Yujin Kim; Moritz Beck-Broichsitter; Ajay K Banga
Journal:  Pharmaceutics       Date:  2019-08-12       Impact factor: 6.321

3.  Application of 2-octyl-cyanoacrylate for corneal perforation and glaucoma filtering bleb leak.

Authors:  Motonori Okabe; Kiyotaka Kitagawa; Toshiko Yoshida; Chika Koike; Takeshi Katsumoto; Etsuko Fujihara; Toshio Nikaido
Journal:  Clin Ophthalmol       Date:  2013-03-28

4.  Suncon medical adhesive is a suitable alternative to fibrin glue in the 23G minimally invasive vitrectomy.

Authors:  Sha Liu; Suyan Li; Zhengpei Zhang; Sujuan Ji; Haiyang Liu
Journal:  Exp Ther Med       Date:  2017-05-29       Impact factor: 2.447

  4 in total

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