| Literature DB >> 16157367 |
René Westerhausen1, Frank Kreuder, Sarah Dos Santos Sequeira, Christof Walter, Wolfgang Woerner, Ralf Arne Wittling, Elisabeth Schweiger, Werner Wittling.
Abstract
The present study aimed to examine how differences in functional lateralisation of language are related to interindividual variations in interhemispheric connectivity. Utilising an fMRI silent word-generation paradigm, 89 left- and right-handed subjects were subdivided into four lateralisation subgroups. Applying morphological and diffusion-tensor MRI, midsagittal cross-sectional area as well as quantitative measures of molecular diffusion (anisotropy, mean diffusion) of the corpus callosum were determined to assess interhemispheric connectivity. Statistical analyses revealed group differences in molecular diffusion but not in callosal size, which may be interpreted to reflect a stronger and/or faster interhemispheric connection in strongly left-lateralised subjects as compared to moderately left-lateralised, bilateral, or moderately right-lateralised subjects.Mesh：
Year: 2005 PMID： 16157367 DOI： 10.1016/j.bandl.2005.07.133
Source DB: PubMed Journal: Brain Lang ISSN： 0093-934X Impact factor: 2.381