OBJECTIVE: The purpose of this study was to determine if there is a difference in perinatal outcome by gender among growth-restricted fetuses. STUDY DESIGN: This was a retrospective cohort study of intrauterine growth restriction (IUGR) singleton pregnancies over a 5-year period. Clinical outcomes compared by gender included preterm delivery, perinatal mortality (PNM), respiratory distress syndrome (RDS), grade 3 or 4 intraventricular hemorrhage (IVH), necrotizing enterocolitis (NEC), and periventricular leukomalacia (PVL). Statistical analysis included bivariate and multivariable techniques. RESULTS: Seven hundred and twenty-seven singleton pregnancies with IUGR were identified. Three hundred and forty-six (47.6%) were males. Birth weight was similar between the groups. After adjusting for maternal demographics, medical history, gestational age, mode of delivery, and antenatal corticosteroids, adverse perinatal outcomes were similar between the groups. Severity of outcomes was also similar between males and females (P = .66). CONCLUSION: Male fetuses with IUGR have similar outcomes when compared with female IUGR fetuses. Gender does not play a role in perinatal outcome in the setting of fetal growth restriction.
OBJECTIVE: The purpose of this study was to determine if there is a difference in perinatal outcome by gender among growth-restricted fetuses. STUDY DESIGN: This was a retrospective cohort study of intrauterine growth restriction (IUGR) singleton pregnancies over a 5-year period. Clinical outcomes compared by gender included preterm delivery, perinatal mortality (PNM), respiratory distress syndrome (RDS), grade 3 or 4 intraventricular hemorrhage (IVH), necrotizing enterocolitis (NEC), and periventricular leukomalacia (PVL). Statistical analysis included bivariate and multivariable techniques. RESULTS: Seven hundred and twenty-seven singleton pregnancies with IUGR were identified. Three hundred and forty-six (47.6%) were males. Birth weight was similar between the groups. After adjusting for maternal demographics, medical history, gestational age, mode of delivery, and antenatal corticosteroids, adverse perinatal outcomes were similar between the groups. Severity of outcomes was also similar between males and females (P = .66). CONCLUSION: Male fetuses with IUGR have similar outcomes when compared with female IUGR fetuses. Gender does not play a role in perinatal outcome in the setting of fetal growth restriction.
Authors: Iris G Streimish; Richard A Ehrenkranz; Elizabeth N Allred; T Michael O'Shea; Karl C K Kuban; Nigel Paneth; Alan Leviton Journal: Early Hum Dev Date: 2012-06-23 Impact factor: 2.079
Authors: Bart Jan Voskamp; Myrthe J C S Peelen; Anita C J Ravelli; Robin van der Lee; Ben W J Mol; Eva Pajkrt; Wessel Ganzevoort; Brenda M Kazemier Journal: Acta Obstet Gynecol Scand Date: 2019-08-30 Impact factor: 3.636
Authors: Bart Jan Voskamp; Brenda M Kazemier; Ewoud Schuit; Ben Willem J Mol; Maarten Buimer; Eva Pajkrt; Wessel Ganzevoort Journal: Obstet Gynecol Int Date: 2014-08-13
Authors: Zoe A Broere-Brown; Maria C Adank; Laura Benschop; Myrte Tielemans; Taulant Muka; Romy Gonçalves; Wichor M Bramer; Josje D Schoufour; Trudy Voortman; Eric A P Steegers; Oscar H Franco; Sarah Schalekamp-Timmermans Journal: Biol Sex Differ Date: 2020-05-11 Impact factor: 5.027