| Literature DB >> 16156521 |
Kosaku Takahashi1, Teruhiko Yoshihara, Kazuhiko Kurosawa.
Abstract
Novel immunosuppressants, ushikulides A and B, were isolated from the culture broth of Streptomyces sp. IUK-102. Ushikulides A and B both have the same molecular formula, determined as C40H68O10. The structures of both compounds were elucidated to be novel 22-membered macrolides. Both compounds showed immunosuppressive activity for murine splenocyte proliferation in vitro.Entities:
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Year: 2005 PMID: 16156521 DOI: 10.1038/ja.2005.55
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN: 0021-8820 Impact factor: 2.649