| Literature DB >> 16156518 |
Nobuo Hosotani1, Kazuo Kumagai, Hiroyuki Nakagawa, Takuro Shimatani, Ikutaro Saji.
Abstract
Two new 24-membered macrolides, SPA-6952A and B, were isolated from the fermentation broth of Streptomyces sp. SPA-6952. The structures of the new macrolides were determined by spectral analyses, including 2D NMR techniques. These compounds exhibited cytotoxic activity against human promyelocytic leukemia HL-60 cells.Entities:
Mesh：
Substances：
Year: 2005 PMID： 16156518 DOI： 10.1038/ja.2005.52
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649