| Literature DB >> 16155609 |
Christophe Nicot1, Robert L Harrod, Vincenzo Ciminale, Genoveffa Franchini.
Abstract
The human T-cell leukemia/lymphoma virus (HTLV) genome, in addition to the structural Gag and Env proteins and retroviral enzymes, carries a region at its 3' end originally designated pX. To date, we know that this region encodes two essential transcriptional and post-transcriptional positive regulators of viral expression, the Tax and Rex proteins, respectively (reviewed elsewhere in this issue). Here, we will review current knowledge of the functions of three additional proteins encoded in the pX region, p12I, p13II, and p30II.Entities:
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Year: 2005 PMID： 16155609 DOI： 10.1038/sj.onc.1208977
Source DB: PubMed Journal: Oncogene ISSN： 0950-9232 Impact factor: 9.867