| Literature DB >> 16154856 |
Wim J E Tissing, Melchior Lauten, Jules P P Meijerink, Monique L den Boer, Jan Willem Koper, Peter Sonneveld, Rob Pieters.
Abstract
In vitro prednisolone resistance is a poor prognostic factor in the treatment of childhood acute lymphoblastic leukemia (ALL). In a cohort of 54 children with ALL, a lower expression of the glucocorticoid receptor (GR), but not the relative expression levels of the GR-alpha, GR-beta and GR-P isoforms, was associated with in vitro prednisolone resistance.Entities:
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Year: 2005 PMID: 16154856
Source DB: PubMed Journal: Haematologica ISSN: 0390-6078 Impact factor: 9.941