Literature DB >> 16154856

Expression of the glucocorticoid receptor and its isoforms in relation to glucocorticoid resistance in childhood acute lymphocytic leukemia.

Wim J E Tissing, Melchior Lauten, Jules P P Meijerink, Monique L den Boer, Jan Willem Koper, Peter Sonneveld, Rob Pieters.   

Abstract

In vitro prednisolone resistance is a poor prognostic factor in the treatment of childhood acute lymphoblastic leukemia (ALL). In a cohort of 54 children with ALL, a lower expression of the glucocorticoid receptor (GR), but not the relative expression levels of the GR-alpha, GR-beta and GR-P isoforms, was associated with in vitro prednisolone resistance.

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Year:  2005        PMID: 16154856

Source DB:  PubMed          Journal:  Haematologica        ISSN: 0390-6078            Impact factor:   9.941


  14 in total

1.  Glucocorticoid receptor knock down reveals a similar apoptotic threshold but differing gene regulation patterns in T-cell and pre-B-cell acute lymphoblastic leukemia.

Authors:  Jason R Schwartz; Purvaba J Sarvaiya; Wayne V Vedeckis
Journal:  Mol Cell Endocrinol       Date:  2010-02-17       Impact factor: 4.102

Review 2.  Tissue-specific glucocorticoid action: a family affair.

Authors:  Katherine L Gross; John A Cidlowski
Journal:  Trends Endocrinol Metab       Date:  2008-09-19       Impact factor: 12.015

3.  Glucocorticoid-induced apoptosis of healthy and malignant lymphocytes.

Authors:  Lindsay K Smith; John A Cidlowski
Journal:  Prog Brain Res       Date:  2010       Impact factor: 2.453

4.  Insights on neoplastic stem cells from gel-based proteomics of childhood germ cell tumors.

Authors:  William E Haskins; Sruthi Eedala; Y L Avinash Jadhav; Manbir S Labhan; Vidya C Pericherla; Elizabeth J Perlman
Journal:  Pediatr Blood Cancer       Date:  2011-07-26       Impact factor: 3.167

5.  Expression of 11beta-hydroxysteroid dehydrogenase 2 contributes to glucocorticoid resistance in lymphoblastic leukemia cells.

Authors:  Shuji Sai; Yuichi Nakagawa; Rie Yamaguchi; Masako Suzuki; Kimiyoshi Sakaguchi; Shuichi Okada; Jonathan R Seckl; Takehiko Ohzeki; Karen E Chapman
Journal:  Leuk Res       Date:  2011-07-26       Impact factor: 3.156

6.  Flow cytometry analysis of glucocorticoid receptor expression and binding in steroid-sensitive and steroid-resistant patients with systemic lupus erythematosus.

Authors:  Juan Du; Min Li; Denghai Zhang; Xiaoyan Zhu; Weiwei Zhang; Wei Gu; Yinglu Feng; Xiaofeng Zhai; Changquan Ling
Journal:  Arthritis Res Ther       Date:  2009-07-14       Impact factor: 5.156

7.  Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells.

Authors:  Esther Hulleman; Karin M Kazemier; Amy Holleman; David J VanderWeele; Charles M Rudin; Mathilde J C Broekhuis; William E Evans; Rob Pieters; Monique L Den Boer
Journal:  Blood       Date:  2008-10-31       Impact factor: 22.113

8.  The SWI/SNF chromatin-remodeling complex and glucocorticoid resistance in acute lymphoblastic leukemia.

Authors:  Nicolas Pottier; Wenjian Yang; Mahfoud Assem; John C Panetta; Deqing Pei; Steven W Paugh; Cheng Cheng; Monique L Den Boer; Mary V Relling; Rob Pieters; William E Evans; Meyling H Cheok
Journal:  J Natl Cancer Inst       Date:  2008-12-09       Impact factor: 13.506

9.  Mechanisms of glucocorticoid resistance in hypereosinophilic syndromes.

Authors:  Kindra Stokes; Pryscilla Yoon; Michelle Makiya; Meheret Gebreegziabher; Nicole Holland-Thomas; JeanAnne Ware; Lauren Wetzler; Paneez Khoury; Amy D Klion
Journal:  Clin Exp Allergy       Date:  2019-10-27       Impact factor: 5.018

Review 10.  Molecular mechanisms regulating glucocorticoid sensitivity and resistance.

Authors:  Katherine L Gross; Nick Z Lu; John A Cidlowski
Journal:  Mol Cell Endocrinol       Date:  2008-10-19       Impact factor: 4.102

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