Literature DB >> 16154387

Onchocerciasis control and elimination: coming of age in resource-constrained health systems.

David H Molyneux1.   

Abstract

During the past three decades, onchocerciasis control has been successful in reducing blindness and skin disease in Africa and the Americas. In this article, I review the control and elimination of Onchocerca volvulus as a public health problem. The success of onchocerciasis control has been the result of secure financing, generous drug donation, effective partnership between stakeholders, and focused operational and implementation research. The future challenges are to ensure sustainability of existing programmes and to increase the level of integration with other health interventions in resource-deficient health systems.

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Year:  2005        PMID: 16154387     DOI: 10.1016/j.pt.2005.08.027

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN: 1471-4922


  9 in total

1.  In a bovine model of onchocerciasis, protective immunity exists naturally, is absent in drug-cured hosts, and is induced by vaccination.

Authors:  Virginia L Tchakouté; Simon P Graham; Siv Aina Jensen; Benjamin L Makepeace; Charles K Nfon; Leo M Njongmeta; Sara Lustigman; Peter A Enyong; Vincent N Tanya; Albert E Bianco; Alexander J Trees
Journal:  Proc Natl Acad Sci U S A       Date:  2006-04-03       Impact factor: 11.205

2.  Onchocerca armillata contains the endosymbiotic bacterium Wolbachia and elicits a limited inflammatory response.

Authors:  Joseph M Neary; Alexander J Trees; David D Ekale; Vincent N Tanya; Udo Hetzel; Benjamin L Makepeace
Journal:  Vet Parasitol       Date:  2010-09-17       Impact factor: 2.738

3.  River blindness: a success story under threat?

Authors:  María-Gloria Basáñez; Sébastien D S Pion; Thomas S Churcher; Lutz P Breitling; Mark P Little; Michel Boussinesq
Journal:  PLoS Med       Date:  2006-09       Impact factor: 11.069

4.  The Mectizan Donation Program - highlights from 2005.

Authors:  Mary M Alleman; Nana A Y Twum-Danso; Björn I Thylefors
Journal:  Filaria J       Date:  2006-09-27

5.  40 Years of the APOC Partnership.

Authors:  Jean-Baptist Roungou; Laurent Yameogo; Chris Mwikisa; Daniel A Boakye; Donald A P Bundy
Journal:  PLoS Negl Trop Dis       Date:  2015-05-14

6.  Preventive chemotherapy as a strategy for elimination of neglected tropical parasitic diseases: endgame challenges.

Authors:  Moses J Bockarie; Louise A Kelly-Hope; Maria Rebollo; David H Molyneux
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2013-06-24       Impact factor: 6.237

Review 7.  Multidimensional complexities of filariasis control in an era of large-scale mass drug administration programmes: a can of worms.

Authors:  David H Molyneux; Adrian Hopkins; Mark H Bradley; Louise A Kelly-Hope
Journal:  Parasit Vectors       Date:  2014-08-15       Impact factor: 3.876

Review 8.  Reaching the last mile: main challenges relating to and recommendations to accelerate onchocerciasis elimination in Africa.

Authors:  Gebremedhin Gebrezgabiher; Zeleke Mekonnen; Delenasaw Yewhalaw; Asrat Hailu
Journal:  Infect Dis Poverty       Date:  2019-07-04       Impact factor: 10.485

9.  Immunisation with a multivalent, subunit vaccine reduces patent infection in a natural bovine model of onchocerciasis during intense field exposure.

Authors:  Benjamin L Makepeace; Siv Aina Jensen; Sandra J Laney; Charles K Nfon; Leo M Njongmeta; Vincent N Tanya; Steven A Williams; Albert E Bianco; Alexander J Trees
Journal:  PLoS Negl Trop Dis       Date:  2009-11-10
  9 in total

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