Septations in chronic spinal cord injury cavities contain axons.

Human spinal cord injury (SCI) can result in progressive degeneration that may continue for many years and lead to the formation of highly septated cystic cavities. This hallmark feature has been reproduced in experimental models, but neither its pathogenesis nor clinically relevant features have been fully elucidated. Here, we show for the first time in a rodent model of chronic SCI that the septations spanning cavities contain axons.