Literature DB >> 16151784

A case of primary botryoid conjunctival rhabdomyosarcoma.

Ennio Polito1, Patrizia Pichierri, Antonio Loffredo, Giacomo Lasorella.   

Abstract

BACKGROUND: Rhabdomyosarcoma is the most common childhood primary orbital malignancy, but the occurrence of this tumour in the conjunctiva is rare.
METHODS: A 14-year-old girl presented with a visible case of conjunctival mass in the left eye. The year before, the patient was referred to another hospital for a biopsy of a conjunctival mesenchymal tumour in the same site, which was periodically checked after the excision. We intervened by partially removing the conjunctival mass.
RESULTS: The histopathology revealed a botryoid rhabdomyosarcoma. The patient underwent chemotherapy and fractionated radiotherapy. The follow-up after three years revealed that the patient remained clinically tumor-free, with no ocular complication from the radiotherapy.
CONCLUSION: It is evident that by not excising the tumour in its entirety it is therefore possible to preserve the underlying rectus muscles and not interfere with ocular motility. Subsequent radiotherapy and chemotherapy helped to destroy any residual tumour. Alternatively, surgical excision of the mass alone could lead to recurrence of the tumour after some months or years.

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Year:  2005        PMID: 16151784     DOI: 10.1007/s00417-005-0085-5

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN: 0721-832X            Impact factor:   3.117


  7 in total

1.  Primary conjunctival rhabdomyosarcoma.

Authors:  Simon F Taylor; Kimberly G Yen; Holly Zhou; Bhupendra C K Patel
Journal:  Arch Ophthalmol       Date:  2002-05

2.  Space-occupying orbital masses in children. A review of 250 consecutive biopsies.

Authors:  J A Shields; B Bakewell; J J Augsburger; L A Donoso; V Bernardino
Journal:  Ophthalmology       Date:  1986-03       Impact factor: 12.079

3.  Subconjunctival rhabdomyosarcoma.

Authors:  M R Levy
Journal:  Am J Ophthalmol       Date:  1968-03       Impact factor: 5.258

4.  Clinical spectrum of primary ophthalmic rhabdomyosarcoma.

Authors:  C L Shields; J A Shields; S G Honavar; H Demirci
Journal:  Ophthalmology       Date:  2001-12       Impact factor: 12.079

5.  Primary conjunctival rhabdomyosarcoma: 2.5 years' follow-up after combined chemotherapy and brachytherapy.

Authors:  W Sekundo; P Roggenkämper; H P Fischer; G Fleischhack; D Flühs; W Sauerwein
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1998-11       Impact factor: 3.117

6.  Embryonal rhabdomyosarcoma of the conjunctiva. A clinicopathologic and immunohistochemical study.

Authors:  J D Cameron; M R Wick
Journal:  Arch Ophthalmol       Date:  1986-08

7.  Embryonal rhabdomyosarcoma presenting as conjunctival tumor.

Authors:  Bénédicte Brichard; Patrick De Potter; Catherine Godfraind; Christiane Vermylen
Journal:  J Pediatr Hematol Oncol       Date:  2003-08       Impact factor: 1.289

  7 in total
  3 in total

Review 1.  Tumors of the ocular surface: A review.

Authors:  Santosh G Honavar; Fairooz P Manjandavida
Journal:  Indian J Ophthalmol       Date:  2015-03       Impact factor: 1.848

2.  Botryoid Rhabdomyosarcoma of the Conjunctiva in a Young Boy.

Authors:  Justin D Pennington; R Joel Welch; Sara E Lally; Jerry A Shields; Ralph C Eagle; Carol L Shields
Journal:  Middle East Afr J Ophthalmol       Date:  2018 Apr-Jun

3.  Primary Conjunctival Rhabdomyosarcoma in a Pediatric Patient.

Authors:  Laura Morales R; Angelina Álvarez; José Esguerra; Maria Camila Prada Avella; Fernando Rojas
Journal:  Cureus       Date:  2019-12-06
  3 in total

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