Literature DB >> 16150131

A study to investigate women's experiences of radiation enteritis following radiotherapy for cervical cancer.

J Abayomi1, J Kirwan, A Hackett, G Bagnall.   

Abstract

BACKGROUND: Radiotherapy remains the standard treatment for cervical cancer, especially for more advanced disease. It is estimated that the prevalence of chronic radiation enteritis (CRE) post-radiotherapy is in the region of 5-15%. However, preliminary studies at the study hospital suggest the problem to be more widespread (C. Israel, unpublished data). AIM: This qualitative study of 10 cervical cancer patients investigates experiences of CRE and its impact on quality of life.
METHODS: Informed volunteers participated in one-to-one tape-recorded in-depth interviews exploring experiences following treatment. These interviews were transcribed verbatim and analysed using NUD*IST Nvivo.
RESULTS: The majority of women reported side-effects from radiotherapy, predominantly diarrhoea. CRE had a significant impact upon the physical, psychological and social aspects of life of sufferers, enforcing some to be virtually housebound. Other sufferers were managing their symptoms with regular medication and/or self-imposed restricted diets. Few of these women had ever sought professional help in dealing with their problems because of embarrassment or reluctance to complain.
CONCLUSIONS: If untreated the side-effects of CRE have a disabling affect on sufferers, who may be reluctant to seek help about their symptoms. Health professionals need to be more pro-active in identifying and caring for sufferers of CRE.

Entities:  

Mesh:

Year:  2005        PMID: 16150131     DOI: 10.1111/j.1365-277X.2005.00633.x

Source DB:  PubMed          Journal:  J Hum Nutr Diet        ISSN: 0952-3871            Impact factor:   3.089


  8 in total

Review 1.  Radiation enteritis.

Authors:  Ali H Harb; Carla Abou Fadel; Ala I Sharara
Journal:  Curr Gastroenterol Rep       Date:  2014

2.  Exploring a link between fatigue and intestinal injury during pelvic radiotherapy.

Authors:  Sofie Jakobsson; Karin Ahlberg; Charles Taft; Tor Ekman
Journal:  Oncologist       Date:  2010-07-28

3.  Argon plasma coagulation for the treatment of hemorrhagic radiation colitis.

Authors:  Mindy C W Lam; Matthew Parliament; Clarence K W Wong
Journal:  Case Rep Gastroenterol       Date:  2012-07-05

4.  Gut microbial dysbiosis may predict diarrhea and fatigue in patients undergoing pelvic cancer radiotherapy: a pilot study.

Authors:  Aiping Wang; Zongxin Ling; Zhixiang Yang; Pawel R Kiela; Tao Wang; Cheng Wang; Le Cao; Fang Geng; Mingqiang Shen; Xinze Ran; Yongping Su; Tianmin Cheng; Junping Wang
Journal:  PLoS One       Date:  2015-05-08       Impact factor: 3.240

5.  Factors associated with quality of life of outpatients with breast cancer and gynecologic cancers and their family caregivers: a controlled study.

Authors:  Abdel W Awadalla; Jude U Ohaeri; Abdullah Gholoum; Ahmed O A Khalid; Hussein M A Hamad; Anila Jacob
Journal:  BMC Cancer       Date:  2007-06-19       Impact factor: 4.430

6.  Evaluation of the psychometric properties of the Functional Assessment of Cancer Therapy-Cervix questionnaire in Brazil.

Authors:  Cristiane Menezes Sirna Fregnani; José Humberto Tavares Guerreiro Fregnani; Maria do Rosário Dias de Oliveira Latorre; Ana Maria de Almeida
Journal:  PLoS One       Date:  2013-10-16       Impact factor: 3.240

Review 7.  Cervical cancer prevention and treatment research in Africa: a systematic review from a public health perspective.

Authors:  Sarah Finocchario-Kessler; Catherine Wexler; May Maloba; Natabhona Mabachi; Florence Ndikum-Moffor; Elizabeth Bukusi
Journal:  BMC Womens Health       Date:  2016-06-04       Impact factor: 2.809

8.  Antibiotic Alleviates Radiation-Induced Intestinal Injury by Remodeling Microbiota, Reducing Inflammation, and Inhibiting Fibrosis.

Authors:  Zhenguo Zhao; Wei Cheng; Wei Qu; Guoyi Shao; Shuanghai Liu
Journal:  ACS Omega       Date:  2020-02-05
  8 in total

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