OBJECTIVE: To describe coexisting medical conditions and lifestyle factors associated with asymptomatic peripheral arterial disease (PAD) in a population of white, African American, and Hispanic patients. STUDY DESIGN AND SETTING: White, African American, and Hispanic patients 50 years or older were recruited for this cross-sectional study from 4 primary care clinics in Houston, TX. Patients with an ankle-brachial index (ABI) < 0.9 and without leg symptoms typical of PAD were diagnosed with asymptomatic PAD. RESULTS: 403 patients were screened for PAD. Of these, 25 (6.2%) had asymptomatic PAD. Compared with patients without PAD, diabetes mellitus ([OR] 3.8; 95% CI 1.6, 9.0) and a history of smoking at least 1 pack of cigarettes per day ([OR] 2.5; 95% CI 1.1, 6.0) were significantly associated with asymptomatic PAD. An interaction effect existed between diabetes mellitus and smoking at least 1 pack of cigarettes per day. Diabetes mellitus combined with heavy smoking showed the highest predicted value positive (15%) and the highest specificity (92%). A lack of both demonstrated low rates for predicting asymptomatic PAD (predicted value positive, 1%). CONCLUSION: The ankle-brachial index could become routine screening among patients with diabetes mellitus and/or who smoke.
OBJECTIVE: To describe coexisting medical conditions and lifestyle factors associated with asymptomatic peripheral arterial disease (PAD) in a population of white, African American, and Hispanic patients. STUDY DESIGN AND SETTING: White, African American, and Hispanic patients 50 years or older were recruited for this cross-sectional study from 4 primary care clinics in Houston, TX. Patients with an ankle-brachial index (ABI) < 0.9 and without leg symptoms typical of PAD were diagnosed with asymptomatic PAD. RESULTS: 403 patients were screened for PAD. Of these, 25 (6.2%) had asymptomatic PAD. Compared with patients without PAD, diabetes mellitus ([OR] 3.8; 95% CI 1.6, 9.0) and a history of smoking at least 1 pack of cigarettes per day ([OR] 2.5; 95% CI 1.1, 6.0) were significantly associated with asymptomatic PAD. An interaction effect existed between diabetes mellitus and smoking at least 1 pack of cigarettes per day. Diabetes mellitus combined with heavy smoking showed the highest predicted value positive (15%) and the highest specificity (92%). A lack of both demonstrated low rates for predicting asymptomatic PAD (predicted value positive, 1%). CONCLUSION: The ankle-brachial index could become routine screening among patients with diabetes mellitus and/or who smoke.
Authors: Ruth E Taylor-Piliae; Joan M Fair; Ann N Varady; Mark A Hlatky; Linda C Norton; Carlos Iribarren; Alan S Go; Stephen P Fortmann Journal: Am Heart J Date: 2011-05 Impact factor: 4.749
Authors: Ning Ding; Yingying Sang; Jingsha Chen; Shoshana H Ballew; Corey A Kalbaugh; Maya J Salameh; Michael J Blaha; Matthew Allison; Gerardo Heiss; Elizabeth Selvin; Josef Coresh; Kunihiro Matsushita Journal: J Am Coll Cardiol Date: 2019-07-30 Impact factor: 24.094
Authors: Tracie C Collins; Susan K Ewing; Susan J Diem; Brent C Taylor; Eric S Orwoll; Steven R Cummings; Elsa S Strotmeyer; Kristine E Ensrud Journal: Circulation Date: 2009-04-20 Impact factor: 29.690
Authors: K R Thankappan; G K Mini; Meena Daivadanam; G Vijayakumar; P S Sarma; Mark Nichter Journal: BMC Public Health Date: 2013-01-18 Impact factor: 3.295