Literature DB >> 1614638

Buthionine sulfoximine, an experimental tool to induce glutathione deficiency: elucidation of glutathione and ascorbate in their role as antioxidants.

H P Broquist1.   

Abstract

The development of buthionine sulfoximine, a selective inhibitor of glutathione biosynthesis, is an important new tool to elucidate the in vivo role of glutathione. Recent investigations have shown that ascorbic acid can serve as an essential antioxidant in the presence of severe glutathione deficiency.

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Year:  1992        PMID： 1614638     DOI： 10.1111/j.1753-4887.1992.tb01298.x

Source DB:  PubMed          Journal:  Nutr Rev        ISSN： 0029-6643            Impact factor:   7.110


  8 in total

1.  Anti-tumour and anti-oxidative potential of diosgenin against 7, 12-dimethylbenz(a)anthracene induced experimental oral carcinogenesis.

Authors:  Kasinathan Rajalingam; Govindasamy Sugunadevi; Mariadoss Arokia Vijayaanand; Janakiraman Kalaimathi; Kathiresan Suresh
Journal:  Pathol Oncol Res       Date:  2011-10-12       Impact factor: 3.201

Review 2.  Regulatory pathways and drugs associated with ferroptosis in tumors.

Authors:  Dan Wang; Le Tang; Yijie Zhang; Guili Ge; Xianjie Jiang; Yongzhen Mo; Pan Wu; Xiangying Deng; Lvyuan Li; Sicheng Zuo; Qijia Yan; Shanshan Zhang; Fuyan Wang; Lei Shi; Xiayu Li; Bo Xiang; Ming Zhou; Qianjin Liao; Can Guo; Zhaoyang Zeng; Wei Xiong; Zhaojian Gong
Journal:  Cell Death Dis       Date:  2022-06-10       Impact factor: 9.685

3.  No evident dose-response relationship between cellular ROS level and its cytotoxicity--a paradoxical issue in ROS-based cancer therapy.

Authors:  Chunpeng Zhu; Wei Hu; Hao Wu; Xun Hu
Journal:  Sci Rep       Date:  2014-05-22       Impact factor: 4.379

4.  Copper-Catalyzed Click Reaction on/in Live Cells.

Authors:  Siheng Li; Lin Wang; Fei Yu; Zhiling Zhu; Dema Shobaki; Haoqing Chen; Mu Wang; Jun Wang; Guoting Qin; Uriel J Erasquin; Li Ren; Yingjun Wang; Chengzhi Cai
Journal:  Chem Sci       Date:  2016-11-25       Impact factor: 9.825

5.  Glutathione Deficiency and Alterations in the Sulfur Amino Acid Homeostasis during Early Postnatal Development as Potential Triggering Factors for Schizophrenia-Like Behavior in Adult Rats.

Authors:  Magdalena Górny; Agnieszka Wnuk; Adrianna Kamińska; Kinga Kamińska; Grażyna Chwatko; Anna Bilska-Wilkosz; Małgorzata Iciek; Małgorzata Kajta; Zofia Rogóż; Elżbieta Lorenc-Koci
Journal:  Molecules       Date:  2019-11-22       Impact factor: 4.411

6.  N-Acetylcysteine and Aripiprazole Improve Social Behavior and Cognition and Modulate Brain BDNF Levels in a Rat Model of Schizophrenia.

Authors:  Zofia Rogóż; Kinga Kamińska; Marta Anna Lech; Elżbieta Lorenc-Koci
Journal:  Int J Mol Sci       Date:  2022-02-15       Impact factor: 5.923

7.  Glutathione Deficiency during Early Postnatal Development Causes Schizophrenia-Like Symptoms and a Reduction in BDNF Levels in the Cortex and Hippocampus of Adult Sprague-Dawley Rats.

Authors:  Marta Anna Lech; Monika Leśkiewicz; Kinga Kamińska; Zofia Rogóż; Elżbieta Lorenc-Koci
Journal:  Int J Mol Sci       Date:  2021-06-08       Impact factor: 5.923

8.  Beyond Warburg effect--dual metabolic nature of cancer cells.

Authors:  Jiansheng Xie; Hao Wu; Chunyan Dai; Qiangrong Pan; Zonghui Ding; Danqing Hu; Bingyan Ji; Yan Luo; Xun Hu
Journal:  Sci Rep       Date:  2014-05-13       Impact factor: 4.379
  8 in total

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