Literature DB >> 16146364

Facile synthesis of highly functionalized N-methyl amino acid esters without side-chain protection.

Kimberly N White1, Joseph P Konopelski.   

Abstract

[reaction: see text] The facile, two-pot synthesis of N-methyl amino acid esters by way of reductive amination is presented. Side chain protection schemes are not required, the starting materials are all commercially available, and the synthetic method is straightforward and affords desired product in very high yield.

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Year:  2005        PMID： 16146364     DOI： 10.1021/ol051441w

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  9 in total

1.  Nature-inspired total synthesis of (-)-fusarisetin A.

Authors:  Jing Xu; Eduardo J E Caro-Diaz; Lynnie Trzoss; Emmanuel A Theodorakis
Journal:  J Am Chem Soc       Date:  2012-03-08       Impact factor: 15.419

2.  Fusarisetin A: Scalable Total Synthesis and Related Studies.

Authors:  Jing Xu; Eduardo J E Caro-Diaz; Michelle H Lacoske; Chao-I Hung; Colin Jamora; Emmanuel A Theodorakis
Journal:  Chem Sci       Date:  2012-08-23       Impact factor: 9.825

3.  Synthesis of a cyclic pentapeptide mimic of the active site His-Tyr cofactor of cytochrome c oxidase.

Authors:  Maximillian E Mahoney; Allen Oliver; Olöf Einarsdóttir; Joseph P Konopelski
Journal:  J Org Chem       Date:  2009-11-06       Impact factor: 4.354

4.  Homotyrosine-containing cyanopeptolins 880 and 960 and anabaenopeptins 908 and 915 from Planktothrix agardhii CYA 126/8.

Authors:  Hilary S Okumura; Benjamin Philmus; Cyril Portmann; Thomas K Hemscheidt
Journal:  J Nat Prod       Date:  2009-01       Impact factor: 4.050

5.  Synthesis of D-abrines by palladium-catalyzed reaction of ortho-iodoanilines with N-Boc-N-methylalanyl-substituted acetaldehyde and acetylene.

Authors:  Paulami Danner; Marius Morkunas; Martin E Maier
Journal:  Org Lett       Date:  2013-04-30       Impact factor: 6.005

6.  Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives.

Authors:  Malcolm W B McCulloch; Gary S Coombs; Nikhil Banerjee; Tim S Bugni; Kendell M Cannon; Mary Kay Harper; Charles A Veltri; David M Virshup; Chris M Ireland
Journal:  Bioorg Med Chem       Date:  2008-11-05       Impact factor: 3.641

7.  (2S,NS)-N-Allyl-N-benzyl-1-hydr-oxy-3-(4-hydroxy-phen-yl)-N-methyl-propan-2-aminium bromide.

Authors:  Hua-Fang Wu; Ying-Gang Luo; Kai-Bei Yu; Guo-Lin Zhang; Xin-Fu Pan
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-07-31

8.  Fermentative Production of N-Methylglutamate From Glycerol by Recombinant Pseudomonas putida.

Authors:  Melanie Mindt; Tatjana Walter; Joe Max Risse; Volker F Wendisch
Journal:  Front Bioeng Biotechnol       Date:  2018-11-09

9.  Synthesis of tryptophan-dehydrobutyrine diketopiperazine and biological activity of hangtaimycin and its co-metabolites.

Authors:  Houchao Xu; Anne Wochele; Minghe Luo; Gregor Schnakenburg; Yuhui Sun; Heike Brötz-Oesterhelt; Jeroen S Dickschat
Journal:  Beilstein J Org Chem       Date:  2022-09-07       Impact factor: 2.544
  9 in total

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