| Literature DB >> 16146357 |
Thanos Andreou1, Anna M Costa, Laia Esteban, Lluïsa Gonzàlez, Gemma Mas, Jaume Vilarrasa.
Abstract
[reaction: see text] The key fragment (2a or 2b) in a total synthesis of the cytotoxic macrolide (-)-amphidinolide K (1) has been achieved from synthons C9-C14 (3) and C15-C22 (4), which have both been prepared from glutamic acid in good overall yields.Entities:
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Year: 2005 PMID： 16146357 DOI： 10.1021/ol051200o
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005