Literature DB >> 16143359

Synthesis of 7alpha-hydroxy-dehydroepiandrosterone and 7beta-hydroxy-dehydroepiandrosterone.

Heping Li1, Hong-Min Liu, Wenzhong Ge, Lihua Huang, Lihong Shan.   

Abstract

The fermentation of dehydroepiandrosterone synthesized from the starting material diosgenin using Mucor racemosus produced 7alpha-hydroxy-dehydroepiandrosterone and 7beta-hydroxy-dehydroepiandrosterone. The bioactivity of the microbial metabolites is also discussed. The species M. racemosus was isolated by screening among stains from soil samples collected from various parts of China.

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Year:  2005        PMID: 16143359     DOI: 10.1016/j.steroids.2005.07.006

Source DB:  PubMed          Journal:  Steroids        ISSN: 0039-128X            Impact factor:   2.668


  3 in total

1.  Distinct Regioselectivity of Fungal P450 Enzymes for Steroidal Hydroxylation.

Authors:  Wei Lu; Jinhui Feng; Xi Chen; Yun-Juan Bao; Yu Wang; Qiaqing Wu; Yanhe Ma; Dunming Zhu
Journal:  Appl Environ Microbiol       Date:  2019-08-29       Impact factor: 4.792

2.  Steroid conversion with CYP106A2 - production of pharmaceutically interesting DHEA metabolites.

Authors:  Daniela Schmitz; Josef Zapp; Rita Bernhardt
Journal:  Microb Cell Fact       Date:  2014-06-05       Impact factor: 5.328

Review 3.  New Insights on Steroid Biotechnology.

Authors:  Lorena Fernández-Cabezón; Beatriz Galán; José L García
Journal:  Front Microbiol       Date:  2018-05-15       Impact factor: 5.640

  3 in total

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