| Literature DB >> 16141061 |
Phillip D Zamore1, Benjamin Haley.
Abstract
Small RNA guides--microRNAs, small interfering RNAs, and repeat-associated small interfering RNAs, 21 to 30 nucleotides in length--shape diverse cellular pathways, from chromosome architecture to stem cell maintenance. Fifteen years after the discovery of RNA silencing, we are only just beginning to understand the depth and complexity of how these RNAs regulate gene expression and to consider their role in shaping the evolutionary history of higher eukaryotes.Mesh：
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Year: 2005 PMID： 16141061 DOI： 10.1126/science.1111444
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728