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Literature DB >> 16140531

A fluorogenic and chromogenic probe that detects the esterase activity of trace copper(II).

Abstract

Bis(picolinoyl)fluorescein, a new fluorogenic and chromogenic probe for monitoring the esterase activity of metal ions, has been synthesized. The probe is highly selective for Cu2+ and is applicable both to quantification of the free ion and detection of esterolytic activity of Cu bound to organic ligands or biomolecules, with a detection limit of 100 nM by fluorimetry.

Entities: Chemical

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Year: 2005 PMID： 16140531 DOI： 10.1016/j.bmcl.2005.07.042

Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823

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Cited

7 in total

1. Reaction-based fluorescent sensor for investigating mobile Zn2+ in mitochondria of healthy versus cancerous prostate cells.

Authors: Wen Chyan; Daniel Y Zhang; Stephen J Lippard; Robert J Radford
Journal: Proc Natl Acad Sci U S A Date: 2013-12-12 Impact factor: 11.205

A fluorogenic and chromogenic probe that detects the esterase activity of trace copper(II).

1. Reaction-based fluorescent sensor for investigating mobile Zn2+ in mitochondria of healthy versus cancerous prostate cells.

2. A Highly Sensitive and Selective Fluorescein-Based Cu²⁺ Probe and Its Bioimaging in Cell.

3. Probing oxidative stress: Small molecule fluorescent sensors of metal ions, reactive oxygen species, and thiols.

4. Synthesis and Photophysical Properties of Fluorescein Esters as Potential Organic Semiconductor Materials.

Review 5. Reaction-based small-molecule fluorescent probes for chemoselective bioimaging.

6. A caged imidazopyrazinone for selective bioluminescence detection of labile extracellular copper(ii).

7. Reaction-Based Probes for Imaging Mobile Zinc in Live Cells and Tissues.

A fluorogenic and chromogenic probe that detects the esterase activity of trace copper(II).

1. Reaction-based fluorescent sensor for investigating mobile Zn2+ in mitochondria of healthy versus cancerous prostate cells.

2. A Highly Sensitive and Selective Fluorescein-Based Cu2+ Probe and Its Bioimaging in Cell.

3. Probing oxidative stress: Small molecule fluorescent sensors of metal ions, reactive oxygen species, and thiols.

4. Synthesis and Photophysical Properties of Fluorescein Esters as Potential Organic Semiconductor Materials.

Review 5. Reaction-based small-molecule fluorescent probes for chemoselective bioimaging.

6. A caged imidazopyrazinone for selective bioluminescence detection of labile extracellular copper(ii).

7. Reaction-Based Probes for Imaging Mobile Zinc in Live Cells and Tissues.

2. A Highly Sensitive and Selective Fluorescein-Based Cu²⁺ Probe and Its Bioimaging in Cell.