Literature DB >> 16139791

Thermophilic cytochrome P450 enzymes.

Clinton R Nishida1, Paul R Ortiz de Montellano.   

Abstract

Thermophilic cytochrome P450 enzymes are of potential interest from structural, mechanistic, and biotechnological points of view. The structures and properties of two such enzymes, CYP119 and CYP175A1, have been investigated and provide the foundation for future work on thermophilic P450 enzymes.

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Year:  2005        PMID: 16139791     DOI: 10.1016/j.bbrc.2005.08.093

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  10 in total

1.  The dynamics of camphor in the cytochrome P450 CYP101D2.

Authors:  Shabana Vohra; Maria Musgaard; Stephen G Bell; Luet-Lok Wong; Weihong Zhou; Philip C Biggin
Journal:  Protein Sci       Date:  2013-08-12       Impact factor: 6.725

2.  Two-dimensional NMR and all-atom molecular dynamics of cytochrome P450 CYP119 reveal hidden conformational substates.

Authors:  Jed N Lampe; Relly Brandman; Santhosh Sivaramakrishnan; Paul R Ortiz de Montellano
Journal:  J Biol Chem       Date:  2010-01-22       Impact factor: 5.157

3.  Active-site residues move independently from the rest of the protein in a 200 ns molecular dynamics simulation of cytochrome P450 CYP119.

Authors:  Relly Brandman; Jed N Lampe; Yigal Brandman; Paul R Ortiz de Montellano
Journal:  Arch Biochem Biophys       Date:  2011-02-26       Impact factor: 4.013

4.  Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography.

Authors:  Debashree Basudhar; Yarrow Madrona; Sylvie Kandel; Jed N Lampe; Clinton R Nishida; Paul R Ortiz de Montellano
Journal:  J Biol Chem       Date:  2015-02-10       Impact factor: 5.157

Review 5.  Hydrocarbon hydroxylation by cytochrome P450 enzymes.

Authors:  Paul R Ortiz de Montellano
Journal:  Chem Rev       Date:  2010-02-10       Impact factor: 60.622

6.  A novel intermediate in the reaction of seleno CYP119 with m-chloroperbenzoic acid.

Authors:  Santhosh Sivaramakrishnan; Hugues Ouellet; Jing Du; Kirsty J McLean; Katalin F Medzihradszky; John H Dawson; Andrew W Munro; Paul R Ortiz de Montellano
Journal:  Biochemistry       Date:  2011-03-22       Impact factor: 3.162

7.  Structural Adaptability Facilitates Histidine Heme Ligation in a Cytochrome P450.

Authors:  John A McIntosh; Thomas Heel; Andrew R Buller; Linda Chio; Frances H Arnold
Journal:  J Am Chem Soc       Date:  2015-09-23       Impact factor: 15.419

8.  Enhanced Activity and Substrate Specificity by Site-Directed Mutagenesis for the P450 119 Peroxygenase Catalyzed Sulfoxidation of Thioanisole.

Authors:  Xiaoyao Wei; Chun Zhang; Xiaowei Gao; Yanping Gao; Ya Yang; Kai Guo; Xi Du; Lin Pu; Qin Wang
Journal:  ChemistryOpen       Date:  2019-07-02       Impact factor: 2.911

9.  Entropic contribution to enhanced thermal stability in the thermostable P450 CYP119.

Authors:  Zhuo Liu; Sara Lemmonds; Juan Huang; Madhusudan Tyagi; Liang Hong; Nitin Jain
Journal:  Proc Natl Acad Sci U S A       Date:  2018-10-08       Impact factor: 11.205

10.  Molecular Dynamics Simulations of a Cytochrome P450 from Tepidiphilus thermophilus (P450-TT) Reveal How Its Substrate-Binding Channel Opens.

Authors:  Abayomi S Faponle; Anupom Roy; Ayodeji A Adelegan; James W Gauld
Journal:  Molecules       Date:  2021-06-12       Impact factor: 4.411

  10 in total

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