Literature DB >> 16139198

Transcriptional regulation: cancer, neurons and the REST.

Judy M Coulson1.   

Abstract

REST/NRSF was first identified as a transcriptional repressor of neuronal genes in non-neuronal cells. Recent studies have now revealed seemingly paradoxical roles for REST/NRSF in neurogenesis, neural plasticity, tumour suppression and cancer progression.

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Year:  2005        PMID： 16139198     DOI： 10.1016/j.cub.2005.08.032

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  63 in total

Review 1.  Moving from the laboratory bench to patients' bedside: considerations for effective therapy with stem cells.

Authors:  Lauren S Sherman; Jessian Munoz; Shyam A Patel; Meneka A Dave; Ilani Paige; Pranela Rameshwar
Journal:  Clin Transl Sci       Date:  2011-10       Impact factor: 4.689

2.  Transformation by E1A oncoprotein involves ubiquitin-mediated proteolysis of the neuronal and tumor repressor REST in the nucleus.

Authors:  Hancheng Guan; Robert P Ricciardi
Journal:  J Virol       Date:  2012-03-14       Impact factor: 5.103

3.  Estrogen coordinates translation and transcription, revealing a role for NRSF in human breast cancer cells.

Authors:  Michael W Bronson; Sara Hillenmeyer; Richard W Park; Alexander S Brodsky
Journal:  Mol Endocrinol       Date:  2010-04-14

Review 4.  In PC12 cells, expression of neurosecretion and neurite outgrowth are governed by the transcription repressor REST/NRSF.

Authors:  Rosalba D'Alessandro; Jacopo Meldolesi
Journal:  Cell Mol Neurobiol       Date:  2010-11-03       Impact factor: 5.046

Review 5.  REST and CoREST are transcriptional and epigenetic regulators of seminal neural fate decisions.

Authors:  Irfan A Qureshi; Solen Gokhan; Mark F Mehler
Journal:  Cell Cycle       Date:  2010-11-15       Impact factor: 4.534

Review 6.  Biological functions of microRNAs: a review.

Authors:  Yong Huang; Xing Jia Shen; Quan Zou; Sheng Peng Wang; Shun Ming Tang; Guo Zheng Zhang
Journal:  J Physiol Biochem       Date:  2010-10-28       Impact factor: 4.158

7.  A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions.

Authors:  Stefanie J Otto; Sean R McCorkle; John Hover; Cecilia Conaco; Jong-Jin Han; Soren Impey; Gregory S Yochum; John J Dunn; Richard H Goodman; Gail Mandel
Journal:  J Neurosci       Date:  2007-06-20       Impact factor: 6.167

8.  Systematic functional characterization of cis-regulatory motifs in human core promoters.

Authors:  Saurabh Sinha; Adam S Adler; Yair Field; Howard Y Chang; Eran Segal
Journal:  Genome Res       Date:  2008-02-06       Impact factor: 9.043

9.  Functional characterization of neural-restrictive silencer element in mouse pituitary adenylate cyclase-activating polypeptide (PACAP) gene expression.

Authors:  Hideki Sugawara; Aiko Tominaga; Kazuhiko Inoue; Yasuo Takeda; Katsushi Yamada; Atsuro Miyata
Journal:  J Mol Neurosci       Date:  2014-06-19       Impact factor: 3.444

10.  The DNA methylation landscape of small cell lung cancer suggests a differentiation defect of neuroendocrine cells.

Authors:  S Kalari; M Jung; K H Kernstine; T Takahashi; G P Pfeifer
Journal:  Oncogene       Date:  2012-08-20       Impact factor: 9.867
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