| Literature DB >> 16138319 |
Rossella Ventura1, Stefano Puglisi-Allegra.
Abstract
Environmental condition such as food restriction has been shown to produce sensitization to the stimulant and rewarding effects of amphetamine in the low responsive DBA/2J genotype. Here, we report that food-restricted DBA/2J mice lose the impulse-independent component of psychostimulant-induced dopamine release in the nucleus accumbens that is replaced totally by impulse-dependent dopamine release. These results indicate for the first time that the crucial effect of environment-induced sensitization is a dramatic increase of the impulse dependent component. Synapse 58:211-214, 2005. (c) 2005 Wiley-Liss, Inc.Entities:
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Year: 2005 PMID: 16138319 DOI: 10.1002/syn.20197
Source DB: PubMed Journal: Synapse ISSN: 0887-4476 Impact factor: 2.562