| Literature DB >> 16138297 |
Lie Li1, Yu-Xin Sheng, Jin-Lan Zhang, Shan-Shan Wang, De-An Guo.
Abstract
A reversed-phase liquid chromatographic method was used to determine the ginsenosides Rg1, Rb1 and Rd of Panax notoginseng in rat tissues (kidney, liver, heart, spleen and lung) after the administration of total saponins of P. notoginseng. The tissue samples were treated with solid-phase extraction prior to HPLC. The calibration curves for the three saponins were linear in the given concentration ranges. The intra-day and inter-day assay coefficients in tissues were between 76 and 120% respectively. The recoveries of all the tissues were higher than 70%. This method was applied to evaluate the distribution of the three major saponins of P. notoginseng in rat tissues. Copyright 2005 John Wiley & Sons, Ltd.Entities:
Mesh：
Substances：
Year: 2006 PMID： 16138297 DOI： 10.1002/bmc.567
Source DB: PubMed Journal: Biomed Chromatogr ISSN： 0269-3879 Impact factor: 1.902