| Literature DB >> 16137880 |
Cai-Ling Wang1, Hong-Qi Li, Wei-Dong Meng, Feng-Ling Qing.
Abstract
3-Trifluoromethylflavonoid derivatives were prepared for the first time by trifluoromethylation of 3-iodoflavonoid derivatives. Other C ring and B ring trifluoromethylated flavonoid derivatives were also prepared. All the compounds were tested for their effect on the U2OS cell cycle in vitro. Bistrifluoromethylated apigenin derivative 13 showed the strongest activity against the cell growth.Entities:
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Year: 2005 PMID： 16137880 DOI： 10.1016/j.bmcl.2005.07.047
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823