Literature DB >> 16137795

Synthesis and antiproliferative activity of 2,6-dibenzylamino-3,5-dicyanopyridines on human cancer cell lines.

Maria Teresa Cocco1, Cenzo Congiu, Valentina Lilliu, Valentina Onnis.   

Abstract

A new series of 2,6-dibenzylamino-3,5-dicyanopyridines were synthesized and evaluated for their in vitro anticancer activity toward cell lines of nine different types of human cancer. Some of newly prepared compounds demonstrated remarkable anticancer activity against most of the tested subpanel tumor cell lines.

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Year:  2005        PMID： 16137795     DOI： 10.1016/j.ejmech.2005.07.005

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  6 in total

1.  Multi-component synthesis of 2-amino-6-(alkyllthio)pyridine-3,5-dicarbonitriles using Zn(II) and Cd(II) metal-organic frameworks (MOFs) under solvent-free conditions.

Authors:  Muralidhara Thimmaiah; Peng Li; Sridhar Regati; Banglin Chen; John Cong-Gui Zhao
Journal:  Tetrahedron Lett       Date:  2012-09-05       Impact factor: 2.415

2.  1-Benzoyl-3-[3-cyano-8-methyl-4-(1-methyl-1H-pyrrol-2-yl)-5,6,7,8-tetra-hydro-quinolin-2-yl]thio-urea.

Authors:  Abdullah M Asiri; Hassan M Faidallah; Abdulrahman O Al-Youbi; Khalid A Alamry; Seik Weng Ng
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-08-27

3.  Crystal structure of 2-benzyl-amino-4-(4-bromo-phen-yl)-6,7-di-hydro-5H-cyclo-penta-[b]pyridine-3-carbo-nitrile.

Authors:  R A Nagalakshmi; J Suresh; S Maharani; R Ranjith Kumar; P L Nilantha Lakshman
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-02-21

4.  A Novel Synthesis of Highly Functionalized Pyridines by a One-Pot, Three-Component Tandem Reaction of Aldehydes, Malononitrile and N-Alkyl-2-cyanoacetamides under Microwave Irradiation.

Authors:  Ramadan Ahmed Mekheimer; Mariam Abdullah Al-Sheikh; Hanadi Yousef Medrasi; Najla Hosain Hassan Alsofyani
Journal:  Molecules       Date:  2018-03-09       Impact factor: 4.411

5.  New 3-Cyano-2-Substituted Pyridines Induce Apoptosis in MCF 7 Breast Cancer Cells.

Authors:  Ahmed Malki; Mona Mohsen; Hassan Aziz; Ola Rizk; Omima Shaban; Mohamed El-Sayed; Zaki A Sherif; Hayam Ashour
Journal:  Molecules       Date:  2016-02-18       Impact factor: 4.411

6.  Design and Preparation of Copper(II)-Mesalamine Complex Functionalized on Silica-Coated Magnetite Nanoparticles and Study of Its Catalytic Properties for Green and Multicomponent Synthesis of Highly Substituted 4H-Chromenes and Pyridines.

Authors:  Hooman Taherkhani; Ali Ramazani; Sami Sajjadifar; Hamideh Aghahossieini; Aram Rezaei
Journal:  ACS Omega       Date:  2022-04-19
  6 in total

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