Literature DB >> 16137168

Malignant fibrous histiocytoma (inflammatory variant) in a child presenting as paraparesis.

Uma N Saikia1, Nalini Gupta, Deepak Bansal, Akshay Kumar Saxena, Kusum Joshi, Radhika Srinivasan.   

Abstract

Malignant fibrous histiocytoma (MFH) in the pediatric age group is extremely rare. Inflammatory variant of MFH is still rarer in children, to the extent that only few case reports of inflammatory variant of MFH are available in the English literature. This report is of a case in a 4-year-old male child, who presented with a chest wall swelling. Fine needle aspiration (FNA) smears showed neutrophilic infiltrate was seen in and around the tumor cells showing a prominent neutrophillic phagocytosis. Possibilities of malignant fibrous histiocytoma, malignant rhabdoid tumor and malignant histiocytosis were offered on cytology. Subsequently, an excision biopsy was performed and was diagnosed as inflammatory variant of MFH. Differential diagnosis of this type of tumor with prominent neutrophillic phagocytosis is discussed with importance of immunostaining for diagnosis. Paraparesis as a presenting feature of inflammatory MFH is rare in children and has not been reported in the literature to the best of our knowledge.

Entities:  

Mesh:

Year:  2004        PMID: 16137168     DOI: 10.1080/15227950490952442

Source DB:  PubMed          Journal:  Fetal Pediatr Pathol        ISSN: 1551-3815            Impact factor:   0.958


  1 in total

1.  Disseminated histiocytic sarcoma in a child: a clinicopathological dichotomy with 8 years survival.

Authors:  Shilpa Sharma; Prasenjit Das; Amit K Dinda; Devendra K Gupta
Journal:  BMJ Case Rep       Date:  2016-05-17
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.