Ying-Quan Luo1, Yu Yang, Shao-Fen Yu. 1. Department of Geriatrics, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Abstract
OBJECTIVE: To investigate the influence of obstructive sleep apnea-hypopnea syndrome (OSAHS) on the QTc interval. METHODS: By the polysomnograph,98 patients were divided into an obstructive sleep apnea-hypopnea syndrome group and a control group. We tested their 24 hour DCG and observed the difference of the heart rate,QT interval and QTc interval at the same time. RESULTS: We compared the heart rate (76 +/- 10 bt/min), QT interval (366 +/- 30 ms), and QTc interval (404 +/- 45 ms) with those of the control group (73 +/- 96 bt/min, 342 +/- 31 ms, 374 +/- 30 ms, respectively). The QT interval and QTc interval significantly differred (P < 0.05). CONCLUSION: The QT interval and QTc interval in the OSAHS group has been prolonged, suggesting OSAHS might be a high risk factor in arrhythmia and sudden death.
OBJECTIVE: To investigate the influence of obstructive sleep apnea-hypopnea syndrome (OSAHS) on the QTc interval. METHODS: By the polysomnograph,98 patients were divided into an obstructive sleep apnea-hypopnea syndrome group and a control group. We tested their 24 hour DCG and observed the difference of the heart rate,QT interval and QTc interval at the same time. RESULTS: We compared the heart rate (76 +/- 10 bt/min), QT interval (366 +/- 30 ms), and QTc interval (404 +/- 45 ms) with those of the control group (73 +/- 96 bt/min, 342 +/- 31 ms, 374 +/- 30 ms, respectively). The QT interval and QTc interval significantly differred (P < 0.05). CONCLUSION: The QT interval and QTc interval in the OSAHS group has been prolonged, suggesting OSAHS might be a high risk factor in arrhythmia and sudden death.
Authors: Shuchita Gupta; Beatriz Cepeda-Valery; Abel Romero-Corral; Abu Shamsuzzaman; Virend K Somers; Gregg S Pressman Journal: J Clin Sleep Med Date: 2012-12-15 Impact factor: 4.062