Ultrastructure of kidney cell population in patients with markers of HCV- and HBV-infections (analysis of biopsy specimens).

Changes in the glomerular, tubular, and interstitial compartments were revealed in kidney biopsy specimens from patients with serological markers of HCV and HBV infections. The dominant change was destruction of the tubular apparatus and atrophy of the tubular epithelium associated with progressive interstitial fibrosis. Our results indicate that kidney disorders constitute patho- and morphogenesis of systemic infection in HCV- and HBV-infected patients.