Literature DB >> 16133786

Untranslated region haplotype in dysbindin gene: analysis in schizophrenia.

V De Luca1, D Voineskos, T Shinkai, G Wong, J L Kennedy.   

Abstract

Genome-scans performed in schizophrenia families have provided evidence for region 6p24-21 where variability may confer susceptibility to schizophrenia. Recent studies have implicated that gene DTNBP1 (dysbindin) in this region is strongly associated with schizophrenia. In a family based association study we investigated three markers located in the untranslated region of the DTNBP1 gene: rs909706, rs1047631 and rs742106. The sample size of our study is 117 families. No biased transmission towards the disorder was detected by haplotype analysis using TRANSMIT.

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Year:  2005        PMID： 16133786     DOI： 10.1007/s00702-005-0338-9

Source DB:  PubMed          Journal:  J Neural Transm (Vienna)        ISSN： 0300-9564            Impact factor:   3.575


  7 in total

1.  A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies.

Authors:  D K Lahiri; J I Nurnberger
Journal:  Nucleic Acids Res       Date:  1991-10-11       Impact factor: 16.971

2.  The family based association test method: strategies for studying general genotype--phenotype associations.

Authors:  S Horvath; X Xu; N M Laird
Journal:  Eur J Hum Genet       Date:  2001-04       Impact factor: 4.246

3.  Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness.

Authors:  C M Drysdale; D W McGraw; C B Stack; J C Stephens; R S Judson; K Nandabalan; K Arnold; G Ruano; S B Liggett
Journal:  Proc Natl Acad Sci U S A       Date:  2000-09-12       Impact factor: 11.205

Review 4.  Searching for schizophrenia genes.

Authors:  N J Bray; M J Owen
Journal:  Trends Mol Med       Date:  2001-04       Impact factor: 11.951

5.  Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain.

Authors:  Cynthia Shannon Weickert; Richard E Straub; Benjamin W McClintock; Mitsuyuki Matsumoto; Ryota Hashimoto; Thomas M Hyde; Mary M Herman; Daniel R Weinberger; Joel E Kleinman
Journal:  Arch Gen Psychiatry       Date:  2004-06

6.  Strong evidence for association between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia in 488 parent-offspring trios from Bulgaria.

Authors:  George Kirov; Dobril Ivanov; Nigel M Williams; Anna Preece; Ivan Nikolov; Radoi Milev; Svetlinka Koleva; Albena Dimitrova; Draga Toncheva; Michael C O'Donovan; Michael J Owen
Journal:  Biol Psychiatry       Date:  2004-05-15       Impact factor: 13.382

7.  Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1).

Authors:  N M Williams; A Preece; D W Morris; G Spurlock; N J Bray; M Stephens; N Norton; H Williams; M Clement; S Dwyer; C Curran; J Wilkinson; V Moskvina; J L Waddington; M Gill; A P Corvin; S Zammit; G Kirov; M J Owen; M C O'Donovan
Journal:  Arch Gen Psychiatry       Date:  2004-04
  7 in total
  3 in total

1.  DTNBP1 (Dystrobrevin binding protein 1) and schizophrenia: association evidence in the 3' end of the gene.

Authors:  Jubao Duan; Maria Martinez; Alan R Sanders; Cuiping Hou; Gregory J Burrell; Aaron J Krasner; Daniel B Schwartz; Pablo V Gejman
Journal:  Hum Hered       Date:  2007-05-02       Impact factor: 0.444

2.  The dystrobrevin binding protein 1 (DTNBP1) gene is associated with schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample.

Authors:  Brien Riley; Po-Hsiu Kuo; Brion S Maher; Ayman H Fanous; Jingchun Sun; Brandon Wormley; F Anthony O'Neill; Dermot Walsh; Zhongming Zhao; Kenneth S Kendler
Journal:  Schizophr Res       Date:  2009-10-02       Impact factor: 4.939

Review 3.  Nature and nurture in neuropsychiatric genetics: where do we stand?

Authors:  Danielle M Dick; Brien Riley; Kenneth S Kendler
Journal:  Dialogues Clin Neurosci       Date:  2010       Impact factor: 5.986
  3 in total

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