PURPOSE: This retrospective study analyzes the predictive factors after curative surgery for papillary thyroid carcinoma (PTC). METHODS: We analyzed 386 patients who underwent a curative operation for PTC in our hospital between 1977 and 1997, subject to the inclusion criteria. RESULTS: According to univariate analysis, pathological lateral cervical lymph node involvement (P < 0.0001), dedifferentiation of the tumor (P < 0.002), male sex (P < 0.0001), a large tumor (P < 0.005), and an age of over 50 years (P < 0.05) were significant factors. Cox's proportional hazard model showed that a man (P < 0.05), aged over 50 years (P < 0.05), who had a large primary tumor (P < 0.05) with dedifferentiation (P < 0.05), and pathological lateral cervical lymph node metastasis (P < 0.005) was more likely to have recurrence of PTC. CONCLUSIONS: Determining whether lymph node metastasis exists could be useful for predicting recurrence in patients who have undergone curative resection of PTC.
PURPOSE: This retrospective study analyzes the predictive factors after curative surgery for papillary thyroid carcinoma (PTC). METHODS: We analyzed 386 patients who underwent a curative operation for PTC in our hospital between 1977 and 1997, subject to the inclusion criteria. RESULTS: According to univariate analysis, pathological lateral cervical lymph node involvement (P < 0.0001), dedifferentiation of the tumor (P < 0.002), male sex (P < 0.0001), a large tumor (P < 0.005), and an age of over 50 years (P < 0.05) were significant factors. Cox's proportional hazard model showed that a man (P < 0.05), aged over 50 years (P < 0.05), who had a large primary tumor (P < 0.05) with dedifferentiation (P < 0.05), and pathological lateral cervical lymph node metastasis (P < 0.005) was more likely to have recurrence of PTC. CONCLUSIONS: Determining whether lymph node metastasis exists could be useful for predicting recurrence in patients who have undergone curative resection of PTC.
Authors: Zubair W Baloch; Julieta E Barroeta; Janet Walsh; Prabodh K Gupta; Virginia A Livolsi; Jill E Langer; Susan J Mandel Journal: Cytojournal Date: 2008-01-31 Impact factor: 2.091
Authors: Seokho Yoon; Young-Sil An; Su Jin Lee; Eu Young So; Jang-Hee Kim; Yoon-Sok Chung; Joon-Kee Yoon Journal: Medicine (Baltimore) Date: 2015-12 Impact factor: 1.817