| Literature DB >> 16132269 |
Yu D Ignatov1, A I Vislobokov, T D Vlasov, M E Kolpakova, K N Mel'nikov, I N Petrishchev.
Abstract
Intracellular dialysis and membrane voltage clamping were used to show that He-Ne laser irradiation of a pond snail neuron at a dose of 0.7 x 10(-4) J (power density 1.5 x 10(2) W/m2) increases the amplitude of the potential-dependent slow potassium current, while a dose of 0.7 x 10(-3) J decreases this current. Bupivacaine suppresses the potassium current. Combined application of laser irradiation at a dose of 0.7 x 10(-3) J increased the blocking effect of 10 microM bupivacaine on the slow potassium current, while an irradiation dose of 0.7 x 10(-4) J weakened the effect of bupivacaine.Entities:
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Year: 2005 PMID： 16132269 DOI： 10.1007/s11055-005-0137-7
Source DB: PubMed Journal: Neurosci Behav Physiol ISSN： 0097-0549