Literature DB >> 16131736

Genes involved in Alzheimer's disease, a survey of possible candidates.

Alessandro Serretti1, Paola Artioli, Roberto Quartesan, Diana De Ronchi.   

Abstract

Alzheimer's disease (AD) is the major cause of dementia in the elderly. It is characterized by a progressive deterioration in memory and cognitive functions, but also behavioral symptoms are common. Many different genes are possibly involved in Alzheimer's Disease: four genetic factors were confirmed in different studies, while at least 50 additional genes were tested with contrasting results. A major aim both for clinician and researchers would be the identification of the genes involved in AD, to better understand the biological mechanism of this disease and consequently to develop appropriate treatments. The aim of this review is to explore genetics of AD.

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Year:  2005        PMID： 16131736     DOI： 10.3233/jad-2005-7410

Source DB:  PubMed          Journal:  J Alzheimers Dis        ISSN： 1387-2877            Impact factor:   4.472


  9 in total

Review 1.  Genetics of Alzheimer disease.

Authors:  Lynn M Bekris; Chang-En Yu; Thomas D Bird; Debby W Tsuang
Journal:  J Geriatr Psychiatry Neurol       Date:  2010-12       Impact factor: 2.680

2.  Serotonin transporter and saitohin genes in risk of Alzheimer's disease and frontotemporal lobar dementia: preliminary findings.

Authors:  Cristina Lorenzi; Alessandra Marcone; Adele Pirovano; Elena Marino; Francesco Cordici; Chiara Cerami; Dario Delmonte; Stefano F Cappa; Placido Bramanti; Enrico Smeraldi
Journal:  Neurol Sci       Date:  2010-09-18       Impact factor: 3.307

Review 3.  Binding between Prion Protein and Aβ Oligomers Contributes to the Pathogenesis of Alzheimer's Disease.

Authors:  Chang Kong; Hao Xie; Zhenxing Gao; Ming Shao; Huan Li; Run Shi; Lili Cai; Shanshan Gao; Taolei Sun; Chaoyang Li
Journal:  Virol Sin       Date:  2019-05-15       Impact factor: 4.327

4.  Amyloid precursor protein 96-110 and beta-amyloid 1-42 elicit developmental anomalies in sea urchin embryos and larvae that are alleviated by neurotransmitter analogs for acetylcholine, serotonin and cannabinoids.

Authors:  Gennady A Buznikov; Lyudmila A Nikitina; Frederic J Seidler; Theodore A Slotkin; Vladimir V Bezuglov; Ivan Milosević; Lidija Lazarević; Ljubica Rogac; Sabera Ruzdijić; Ljubisa M Rakić
Journal:  Neurotoxicol Teratol       Date:  2008-05-16       Impact factor: 3.763

5.  Neuronal models for studying tau pathology.

Authors:  Thorsten Koechling; Filip Lim; Felix Hernandez; Jesus Avila
Journal:  Int J Alzheimers Dis       Date:  2010-07-19

6.  Dementia with Lewy bodies: Definition, diagnosis, and pathogenic relationship to Alzheimer's disease.

Authors:  Robert E Mrak; W Sue T Griffin
Journal:  Neuropsychiatr Dis Treat       Date:  2007       Impact factor: 2.570

7.  Network Topology Analysis of Post-Mortem Brain Microarrays Identifies More Alzheimer's Related Genes and MicroRNAs and Points to Novel Routes for Fighting with the Disease.

Authors:  Sreedevi Chandrasekaran; Danail Bonchev
Journal:  PLoS One       Date:  2016-01-19       Impact factor: 3.240

Review 8.  The biological pathways of Alzheimer disease: a review.

Authors:  Marco Calabrò; Carmela Rinaldi; Giuseppe Santoro; Concetta Crisafulli
Journal:  AIMS Neurosci       Date:  2020-12-16

Review 9.  Genetic aspects of Alzheimer disease.

Authors:  Thomas D Bird
Journal:  Genet Med       Date:  2008-04       Impact factor: 8.822
  9 in total

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