Literature DB >> 16130900

Establishment and characterization of human malignant lymphoma cell line derived from uterine cervix.

Kazushige Kiguchi1, Isamu Ishiwata, Chieko Ishiwata, Emiko Ishiwata, Yutaka Koshitaka, Masanori Iwata, Yoshiko Okuda, Youichi Kobayashi, Yasuna Wada, Bunpei Ishizuka, Hiroshi Ishikawa.   

Abstract

Human uterine cervical malignant lymphoma (B-cell type) was cultured and the cell line (HIUML) was newly established. The HIUML cells were round in shape and had a tendency to make floating clusters. The cells had a smooth surface or protrusion on the margin of the cytoplasm, and proliferate in floatation. The population doubling time was about 32 hours and 42 or more passages were successfully observed in two years. The HIUML cells were not transplantable into nude mice but were successfully done in the cheek pouch of hamster with formation of malignant lymphoma. Epstein-Barr virus was detected in the HIUML cells.

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Year:  2005        PMID: 16130900     DOI: 10.1111/j.1749-0774.2005.tb00057.x

Source DB:  PubMed          Journal:  Hum Cell        ISSN: 0914-7470            Impact factor:   4.174


  9 in total

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  9 in total

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