Literature DB >> 16130842

Prevalence of vulvar lichen sclerosus in a general gynecology practice.

Andrew T Goldstein1, Stanley C Marinoff, Kurt Christopher, Monica Srodon.   

Abstract

OBJECTIVE: To describe the rate of vulvar lichen sclerosus in 1 general gynecology practice. STUDY
DESIGN: A database of 1,675 consecutive patients presenting in a 3-year period to a general gynecology practice was utilized to identify women with lichen sclerosus. Data included age, menopausal status, symptoms and physical examination findings. Pathology specimens were reexamined by a gynecologic pathologist to confirm the diagnosis of lichen sclerosus.
RESULTS: Of the 1,675 patients, 28 (1.7%) had biopsy-proven vulvar lichen sclerosus. Nine patients been diagnosed previously, and 19 were new cases. The mean age at diagnosis was 52.6 years (SD +/- 15.9) versus 37.1 years (SD +/- 16.4) for those without lichen sclerosus (p < 0.001). Fifteen of the 28 patients (54%) were post-menopausal at the time of diagnosis. Of the 19 women with newly diagnosed lichen sclerosus, 8 (42%) were symptomatic. Of the 11 asymptomatic women, 7 (64%) had scarring of the clitoral prepuce or resorption of the labia minora.
CONCLUSION: The rate of vulvar lichen sclerosus in 1 general gynecology private practice is approximately 1.7%. Clinicians must maintain a high index of suspicion to make the diagnosis, as at least one third of patients may be asymptomatic.

Entities:  

Mesh:

Year:  2005        PMID: 16130842

Source DB:  PubMed          Journal:  J Reprod Med        ISSN: 0024-7758            Impact factor:   0.142


  27 in total

Review 1.  Pediatric Lichen Sclerosus: A Review of the Literature and Management Recommendations.

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Review 4.  [Lichen sclerosus in children].

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5.  Lower Urinary Tract and Functional Bowel Symptoms in Women With Vulvar Diseases and Controls.

Authors:  Carolyn W Swenson; Stacy B Menees; Hope K Haefner; Mitchell B Berger
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6.  History of Abuse in Women With Vulvar Pruritus, Vulvodynia, and Asymptomatic Controls.

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8.  Fractionated Carbon Dioxide Laser for the Treatment of Vulvar Lichen Sclerosus: A Randomized Controlled Trial.

Authors:  Leia Mitchell; Andrew T Goldstein; Debra Heller; Theodora Mautz; Chelsea Thorne; So Yeon Joyce Kong; Maria E Sophocles; Hillary Tolson; Jill M Krapf
Journal:  Obstet Gynecol       Date:  2021-06-01       Impact factor: 7.661

9.  The Effect of Lipofilling and Platelet-Rich Plasma on Patients with Moderate-Severe Vulvar Lichen Sclerosus who were Non-Responders to Topical Clobetasol Propionate: A Randomized Pilot Study.

Authors:  P Gutierrez-Ontalvilla; F Giner; L Vidal; M Iborra
Journal:  Aesthetic Plast Surg       Date:  2022-01-20       Impact factor: 2.326

Review 10.  Diagnosis and treatment of lichen sclerosus: an update.

Authors:  Susanna K Fistarol; Peter H Itin
Journal:  Am J Clin Dermatol       Date:  2013-02       Impact factor: 7.403

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